Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 3/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.43 |
| ▸ | SLC28A2 | O43868 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.38 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068569 | 0.93 | ADORA1 (0.44) | PI4KAPI4K2BPI4K2API4KBSLC28A2 | |
| SCHEMBL9705275 | 0.90 | ADORA3 (0.46) | PI4KAPI4K2BPI4K2API4KBSLC28A2 | |
| SCHEMBL10381790 | 0.87 | ADORA1 (0.43) | PI4KAPI4K2BPI4K2API4KBSLC28A2 | |
| SCHEMBL6852710 | 0.83 | ADORA1 (0.48) | PI4KAPI4K2BPI4K2API4KBSLC28A2 | |
| SCHEMBL674400 | 0.83 | ADORA1 (0.48) | PI4KAPI4K2BPI4K2API4KBSLC28A2 | |
| SCHEMBL31645122 | 0.81 | ADORA1 (0.45) | ADORA1ADORA2AADORA3SMN1; SMN2 | |
| SCHEMBL7812798 | 0.81 | ADORA1 (0.40) | PI4KAPI4K2BPI4K2API4KBSLC28A2 | |
| SCHEMBL1068353 | 0.80 | ADORA2A (0.41) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL16496887 | 0.80 | TYMP (0.35) | ADORA1ADORA2AADORA2BADORA3GAPDH | |
| SCHEMBL8970900 | 0.78 | SLC29A1 (0.37) | ADORA1ADORA2AADORA2BADORA3SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7083987-B2 | Activity based probe analysis | ACTIVX BIOSCIENCES, INC. (US) | 2006-08-01 | — | — | US | disclosed |
| EP-1364209-A4 | ACTIVITY BASED PROBE ANALYSIS | ACTIVX BIOSCIENCES INC (US) | 2004-04-14 | — | — | EP | disclosed |
| EP-1364209-A2 | ACTIVITY BASED PROBE ANALYSIS | Activx Biosciences, Inc. (US) | 2003-11-26 | — | — | EP | disclosed |
| US-20030175986-A1 | Activity based probe analysis | ACTIVX BIOSCIENCES, INC. | 2003-09-18 | — | — | US | disclosed |
| US-20030134303-A1 | Adenine nucleotide-binding protein-directed probes, and methods of their synthesis and use | ACTIVX BIOSCIENCES, INC, | 2003-07-17 | — | — | US | disclosed |
| WO-2003050248-A2 | ADENINE NUCLEOTIDE-BINDING PROTEIN-DIRECTED PROBES AND METHODS OF THEIR SYNTHESIS AND USE | ACTIVX BIOSCIENCES, INC. (US) | 2003-06-19 | — | — | WO | disclosed |
| WO-2002063271-A2 | ACTIVITY BASED PROBE ANALYSIS | ACTIVX BIOSCIENCES, INC. (US) | 2002-08-15 | — | — | WO | disclosed |