Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859687 | 1.00 | MEN1 (0.47) | MEN1KMT2AHSD11B1OPRM1OPRL1 | |
| SCHEMBL5859679 | 1.00 | MEN1 (0.47) | MEN1KMT2AHSD11B1OPRM1OPRL1 | |
| SCHEMBL8775328 | 0.79 | KMT2A (0.54) | MEN1KMT2AOPRM1OPRL1OPRK1 | |
| SCHEMBL8775485 | 0.79 | KMT2A (0.54) | MEN1KMT2AOPRM1OPRL1OPRK1 | |
| SCHEMBL12247772 | 0.79 | KMT2A (0.54) | MEN1KMT2AOPRM1OPRL1OPRK1 | |
| SCHEMBL1190299 | 0.78 | KMT2A (0.50) | MEN1KMT2AOPRM1OPRL1OPRK1 | |
| SCHEMBL1190301 | 0.78 | KMT2A (0.50) | MEN1KMT2AOPRM1OPRL1OPRK1 | |
| SCHEMBL12492369 | 0.74 | KMT2A (0.58) | MEN1KMT2AOPRM1OPRL1OPRK1 | |
| SCHEMBL12492368 | 0.74 | KMT2A (0.58) | MEN1KMT2AOPRM1OPRL1OPRK1 | |
| SCHEMBL1189753 | 0.73 | KMT2A (0.61) | MEN1KMT2AOPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109350-B2 | Process for the preparation of optically active amines or salts thereof | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2006-09-19 | — | — | US | disclosed |
| US-20040235928-A1 | Process for the preparation of optically active amines or salts thereof | DAICEL CHEMICAL INDUSTRIES, LTD. | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235928-A1 | Process for the preparation of optically active amines or salts thereof | RER1, H1-0, H1-2 | MEN1 511/4885KMT2A 228/4885HSD11B1 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.