Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.63 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.63 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859165 | 0.91 | NOTUM (0.59) | ALDH1A1GAACHRM2CHRM4CHRM1 | |
| SCHEMBL21248553 | 0.86 | CHRM2 (0.65) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL5250240 | 0.86 | CHRM2 (0.60) | ALDH1A1GAACHRM2CHRM4CHRM1 | |
| SCHEMBL9974151 | 0.83 | CHRM2 (0.68) | ALDH1A1GAACHRM2CHRM4CHRM1 | |
| SCHEMBL20340248 | 0.82 | ALDH1A1 (0.59) | ALDH1A1GAACHRM2CHRM4CHRM1 | |
| SCHEMBL14564376 | 0.82 | CHRM2 (0.67) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL1102038 | 0.81 | CHRM2 (0.70) | ALDH1A1GAACHRM2CHRM4CHRM1 | |
| SCHEMBL18860376 | 0.81 | CHRM2 (0.57) | ALDH1A1GAACHRM2CHRM4CHRM1 | |
| SCHEMBL6233823 | 0.81 | ALDH1A1 (0.44) | ALDH1A1GAACHRM2CHRM4CHRM1 | |
| SCHEMBL6234280 | 0.81 | ALDH1A1 (0.44) | ALDH1A1GAACHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8333345-A | — | — | None | — | — | JP | disclosed |
| US-10188671-B2 | Boron-dipyrrin complex and medicament containing the same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2019-01-29 | — | — | US | disclosed |
| US-20180042948-A1 | BORON-DIPYRRIN COMPLEX AND MEDICAMENT CONTAINING THE SAME | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2018-02-15 | — | — | US | disclosed |
| US-20180042948-A1 | BORON-DIPYRRIN COMPLEX AND MEDICAMENT CONTAINING THE SAME | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2018-02-15 | — | — | US | disclosed |
| US-7109222-B2 | Compounds that modulate PPAR activity and methods of preparation | WARNER-LAMBERT COMPANY, LLC (US) | 2006-09-19 | — | — | US | disclosed |
| US-20050113422-A1 | Compounds that modulate PPAR activity and methods of preparation | CHENG XUE-MIN (US) | 2005-05-26 | — | — | US | disclosed |
| US-20050107442-A1 | Compounds that modulate PPAR activity and methods of preparation | CHENG XUE-MIN (US) | 2005-05-19 | — | — | US | disclosed |
| US-6867224-B2 | Compounds that modulate PPAR activity and methods of preparation | WARNER-LAMBERT COMPANY (US) | 2005-03-15 | — | — | US | disclosed |
| EP-1480641-A1 | SUBSTITUTED THIAZOLES AND OXAZOLES THAT MODULATE PPAR ACTIVITY | WARNER-LAMBERT COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| US-20030207915-A1 | Compounds that modulate PPAR activity and methods of preparation | CHENG XUE-MIN (US) | 2003-11-06 | — | — | US | disclosed |
| WO-2003074051-A1 | SUBSTITUTED THIAZOLES AND OXAZOLES THAT MODULATE PPAR ACTIVITY | WARNER-LAMBERT COMPANY LLC (GB) | 2003-09-12 | — | — | WO | disclosed |
| JP-H08333345-A | SYNTHESIS OF OPTICALLY ACTIVE 1,2,3,4-TETRAHYDROQUINONLINE-2-ACETIC ACID ESTERS BY ASYMMETRIC HYDROGENATION REACTION | SUMITOMO PHARMACEUT CO LTD | 1996-12-17 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10188671-B2 | Boron-dipyrrin complex and medicament containing the same | IAPP, APP, APBA1 | ALDH1A1 2870/4885GAA 429/4885CHRM2 1889/4885 |
| US-20180042948-A1 | BORON-DIPYRRIN COMPLEX AND MEDICAMENT CONTAINING THE SAME | CD79B, APP, BCHE | ALDH1A1 4154/4885GAA 2043/4885CHRM2 95/4885 |
| US-20050113422-A1 | Compounds that modulate PPAR activity and methods of preparation | PPARA, PPARD, PPARG | ALDH1A1 845/4885GAA 866/4885CHRM2 1471/4885 |
| US-20030207915-A1 | Compounds that modulate PPAR activity and methods of preparation | PPARA, PPARD, PPARG | ALDH1A1 845/4885GAA 866/4885CHRM2 1471/4885 |
| US-20050107442-A1 | Compounds that modulate PPAR activity and methods of preparation | PPARA, PPARD, PPARG | ALDH1A1 845/4885GAA 866/4885CHRM2 1471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.