Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11779390 | 0.82 | MAPT (0.45) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL17093302 | 0.78 | MAPT (0.45) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL6874329 | 0.78 | MAPT (0.45) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL20184853 | 0.78 | CYP2D6 (0.46) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL7019907 | 0.78 | MAPT (0.45) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL17582896 | 0.78 | CYP2D6 (0.46) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL20184852 | 0.78 | CYP2D6 (0.46) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL9683891 | 0.78 | CYP2D6 (0.46) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL6529290 | 0.77 | ALDH1A1 (0.41) | MAPTKMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL5860569 | 0.76 | MAPT (0.44) | MAPTKMT2ACYP2C19HIF1AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060471-B2 | Stereoselective chemoenzymatic process for the preparation of optically enriched phenylglycidates as precursors of taxol side chain | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2006-06-13 | — | — | US | disclosed |