Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12884227 | 0.81 | CYP2D6 (0.47) | ALDH1A1ALOX15CYP2C19CYP2D6HSD17B10 | |
| SCHEMBL3959121 | 0.81 | CYP2D6 (0.47) | ALDH1A1ALOX15CYP2C19CYP2D6HSD17B10 | |
| SCHEMBL28365356 | 0.81 | ALDH1A1 (0.44) | ALDH1A1ALOX15CYP2C19CYP2D6HSD17B10 | |
| SCHEMBL27279067 | 0.79 | ALDH1A1 (0.42) | ALDH1A1ALOX15CYP2C19CYP2D6HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL27615498 | 0.79 | CYP2D6 (0.45) | ALDH1A1ALOX15CYP2C19CYP2D6HSD17B10 | |
| SCHEMBL9271121 | 0.77 | ALDH1A1 (0.41) | ALDH1A1ALOX15CYP2C19CYP2D6HSD17B10 | |
| SCHEMBL17586598 | 0.77 | ALDH1A1 (0.41) | ALDH1A1ALOX15CYP2C19CYP2D6HSD17B10 | |
| SCHEMBL5860190 | 0.77 | MAPT (0.44) | ALDH1A1ALOX15CYP2C19CYP2D6ESR1 | |
| SCHEMBL4354021 | 0.76 | MAPK1 (0.42) | ALDH1A1ALOX15CYP2C19CYP2D6HSD17B10 | |
| SCHEMBL487167 | 0.76 | CYP3A4 (0.47) | ALDH1A1ALOX15CYP2C19CYP2D6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455483-B2 | Compounds—801 | ASTRAZENECA AB (SE) | 2013-06-04 | — | — | US | disclosed |
| US-20110053909-A1 | Compounds - 801 | PULMAGEN THERAPEUTICS (SYNERGY) LIMITED (GB) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053909-A1 | Compounds - 801 | ADRA2C, ADRB2, ADRB1 | ALDH1A1 264/4885ALOX15 2508/4885CYP2C19 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.