SCHEMBL5860360

SCHEMBL5860360

O=[N+]([O-])c1ccccc1COc1c(O)cccc1F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.49
HTR1A P08908 1/20 0.45
ADRA1D P25100 1/20 0.45
ADRA1A P35348 1/20 0.45
ADRA1B P35368 1/20 0.45
ALDH1A1 P00352 5/20 0.44
HTT P42858 1/20 0.44
GPR35 Q9HC97 2/20 0.43
TSHR P16473 1/20 0.43
ALDH3A1 P30838 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5594953 0.79 MAOB (0.55) MAOBHTR1AADRA1DADRA1AADRA1B
SCHEMBL16273630 0.78 MAOB (0.49) MAOBHTR1AADRA1DADRA1AADRA1B
SCHEMBL16273631 0.76 MAOB (0.47) MAOBHTR1AADRA1DADRA1AADRA1B
SCHEMBL16273614 0.74 MAOB (0.48) MAOBHTR1AADRA1DADRA1AADRA1B
SCHEMBL3088462 0.74 HTR1A (0.50) HTR1AADRA1DADRA1AADRA1BALDH1A1
SCHEMBL3411094 0.74 HTR1A (0.50) MAOBHTR1AADRA1DADRA1AADRA1B
SCHEMBL9489214 0.74 MAOB (0.72) MAOBHTR1AADRA1DADRA1AADRA1B
SCHEMBL17616589 0.74 MAOB (0.47) MAOBHTR1AADRA1DADRA1AADRA1B
SCHEMBL6823290 0.73 MAOB (0.49) MAOBHTR1AADRA1DADRA1AADRA1B
SCHEMBL16273625 0.73 MAOB (0.49) MAOBHTR1AADRA1DADRA1AADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060214139-A1 Methods for producing a dielectric, dielectric having self-generating pores, monomer for porous dielectrics, process for preparing poly-o-hydroxyamides, process for preparing ploybenzoxazoles, and processes for producing an electronic component INFINEON TECHNOLOGIES AG 2006-09-28 US disclosed
US-7108807-B2 Methods for producing a dielectric, dielectric having self-generating pores, monomer for porous dielectrics, process for preparing poly-o-hydroxyamides, process for preparing polybenzoxazoles, and processes for producing an electronic component INFINEON TECHNOLOGIES AG (DE) 2006-09-19 US disclosed
US-6861560-B2 Bis-o-aminophenols and processes for producing bis-o-aminophenols INFINEON TECHNOLOGIES AG (DE) 2005-03-01 US disclosed
US-6824949-B2 SELF-CONDENSATION OF AN O-AMINOPHENOLCARBOXYLIC ACID AND REACTION WITH BIS-O-AMINOPHENOLS ALONG WITH DICARBOXYLIC ACID AND ACETYLENE COMPOUNDS; HIGH RESISTANCE AGAINST THE DIFFUSION OF METALS INFINEON TECHNOLOGIES AG (DE) 2004-11-30 US disclosed
US-20040049081-A1 Bis-o-aminophenols and processes for producing bis-o-aminophenols POLARIS INNOVATIONS LIMITED (IE) 2004-03-11 US disclosed
US-20040028821-A1 Methods for producing a dielectric, dielectric having self-generating pores, monomer for porous dielectrics, process for preparing poly-o-hydroxyamides, process for preparing polybenzoxazoles, and processes for producing an electronic component POLARIS INNOVATIONS LIMITED (IE) 2004-02-12 US disclosed
US-20020086968-A1 Polybenzoxazole precursors, photoresist solution, polybenzoxazole, and process for preparing a polybenzoxazole precursor POLARIS INNOVATIONS LIMITED (IE) 2002-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040049081-A1 Bis-o-aminophenols and processes for producing bis-o-aminophenols DDC, DDT, NDC1 MAOB 117/4885HTR1A 811/4885ADRA1D 903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.