Ethylene

Ethylene

SCHEMBL5860683

C=C.COC(=O)C(O)CC(=O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.48
SLC22A6 Q4U2R8 1/20 0.40
KMT2A Q03164 2/20 0.36
MAPT P10636 1/20 0.35
GABRR1 P24046 2/20 0.34
LMNA P02545 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
GPR84 Q9NQS5 4/20 0.32
PGD P52209 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL206973 0.95 SMN1; SMN2 (0.52) SMN1; SMN2SLC22A6KMT2AMAPTGABRR1
SCHEMBL9040323 0.95 SMN1; SMN2 (0.52) SMN1; SMN2SLC22A6KMT2AMAPTGABRR1
SCHEMBL222024 0.95 SMN1; SMN2 (0.52) SMN1; SMN2SLC22A6KMT2AMAPTGABRR1
Ammonia Solution, Strong SCHEMBL21219123 0.93 SMN1; SMN2 (0.50) SMN1; SMN2SLC22A6KMT2AMAPTGABRR1
SCHEMBL10933476 0.93 SMN1; SMN2 (0.50) SMN1; SMN2SLC22A6KMT2AMAPTGABRR1
Acrylamide SCHEMBL28172860 0.85 TSHR (0.39) SMN1; SMN2SLC22A6KMT2AGABRR1LMNA
Acrylic Acid Ethyl Ester SCHEMBL5860702 0.83 TSHR (0.40) SMN1; SMN2MAPTLMNA
Ethylene SCHEMBL3909087 0.81 SMN1; SMN2 (0.52) SMN1; SMN2SLC22A6MAPTGABRR1LMNA
SCHEMBL8627026 0.80 SMN1; SMN2 (0.36) SMN1; SMN2SLC22A6KMT2AMAPTCA1
SCHEMBL10871522 0.78 TET2 (0.59) SMN1; SMN2KMT2ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7001538-B2 PTC composition and PTC device comprising the same SHINWHA INTERTEK CORPORATION (KR) 2006-02-21 US disclosed
US-20040099846-A1 Ptc composition and ptc device comprising the same SHINWHA INTERTEK CORP. (KR) 2004-05-27 US disclosed
WO-2002080200-A1 PTC COMPOSITION AND PTC DEVICE COMPRISING THE SAME SHINWHA INTERTEK CORP. (KR) 2002-10-10 WO disclosed