Acrylic Acid Ethyl Ester

Acrylic Acid Ethyl Ester

SCHEMBL5860702

C=C.C=CC(=O)OCC.COC(=O)C(O)CC(=O)O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.40
HPGD P15428 1/20 0.39
HCAR2 Q8TDS4 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.34
ALDH1A1 P00352 5/20 0.34
TP53 P04637 3/20 0.34
HIF1A Q16665 3/20 0.34
CYP3A4 P08684 2/20 0.34
HSD17B10 Q99714 1/20 0.34
THRB P10828 2/20 0.33
CYP2D6 P10635 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MAPK1 P28482 1/20 0.32
EGLN1 Q9GZT9 1/20 0.31
MDM4 O15151 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
MDM2 Q00987 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL5860683 0.83 SMN1; SMN2 (0.48) SMN1; SMN2LMNAMAPT
Acrylic Acid Ethyl Ester SCHEMBL6900588 0.81 TSHR (0.37) TSHRHPGDHCAR2SMN1; SMN2ALDH1A1
Acrylic Acid Ethyl Ester SCHEMBL28881898 0.80 TSHR (0.48) TSHRHPGDHCAR2SMN1; SMN2ALDH1A1
Acrylamide SCHEMBL28172860 0.80 TSHR (0.39) TSHRSMN1; SMN2ALDH1A1LMNA
SCHEMBL206973 0.79 SMN1; SMN2 (0.52) TSHRSMN1; SMN2LMNAMAPT
SCHEMBL9040323 0.79 SMN1; SMN2 (0.52) TSHRSMN1; SMN2LMNAMAPT
SCHEMBL222024 0.79 SMN1; SMN2 (0.52) TSHRSMN1; SMN2LMNAMAPT
Acrylic Acid Ethyl Ester SCHEMBL3872006 0.77 TSHR (0.50) TSHRHPGDHCAR2SMN1; SMN2ALDH1A1
Acrylic Acid Ethyl Ester SCHEMBL5857911 0.77 TSHR (0.50) TSHRHPGDHCAR2SMN1; SMN2ALDH1A1
Ammonia Solution, Strong SCHEMBL21219123 0.77 SMN1; SMN2 (0.50) TSHRSMN1; SMN2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7001538-B2 PTC composition and PTC device comprising the same SHINWHA INTERTEK CORPORATION (KR) 2006-02-21 US disclosed
US-20040099846-A1 Ptc composition and ptc device comprising the same SHINWHA INTERTEK CORP. (KR) 2004-05-27 US disclosed
WO-2002080200-A1 PTC COMPOSITION AND PTC DEVICE COMPRISING THE SAME SHINWHA INTERTEK CORP. (KR) 2002-10-10 WO disclosed