SCHEMBL206973

SCHEMBL206973

COC(=O)C(O)CC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.52
SLC22A6 Q4U2R8 1/20 0.43
KMT2A Q03164 2/20 0.38
MAPT P10636 1/20 0.38
GABRR1 P24046 2/20 0.37
LMNA P02545 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 1/20 0.34
GPR84 Q9NQS5 3/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9040323 1.00 SMN1; SMN2 (0.52) SMN1; SMN2SLC22A6KMT2AMAPTGABRR1
SCHEMBL222024 1.00 SMN1; SMN2 (0.52) SMN1; SMN2SLC22A6KMT2AMAPTGABRR1
Ammonia Solution, Strong SCHEMBL21219123 0.98 SMN1; SMN2 (0.50) SMN1; SMN2SLC22A6KMT2AMAPTGABRR1
SCHEMBL10933476 0.98 SMN1; SMN2 (0.50) SMN1; SMN2SLC22A6KMT2AMAPTGABRR1
Ethylene SCHEMBL5860683 0.95 SMN1; SMN2 (0.48) SMN1; SMN2SLC22A6KMT2AMAPTGABRR1
Acrylamide SCHEMBL28172860 0.84 TSHR (0.39) SMN1; SMN2SLC22A6KMT2AGABRR1LMNA
SCHEMBL8627026 0.84 SMN1; SMN2 (0.36) SMN1; SMN2SLC22A6KMT2AMAPTTSHR
SCHEMBL1691025 0.80 TSHR (0.43) SMN1; SMN2KMT2AMAPTTSHRCA1
SCHEMBL8060426 0.80 ALDH1A1 (0.42) SMN1; SMN2KMT2ALMNATDP1TSHR
SCHEMBL1823637 0.80 TSHR (0.43) SMN1; SMN2KMT2AMAPTTSHRCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111296-A1 ELECTROLYTE COMPOSITIONS AND ELECTROCHEMICAL DEVICES USING THE SAME II-VI DELAWARE, INC. (US) 2025-05-30 WO claimed
CN-119638965-B Polyester microparticles, process for producing the same, and injection-filled article 广东粤港澳大湾区黄埔材料研究院 2025-05-13 CN claimed
CN-119799159-A Bio-based UV curing release agent, preparation method thereof and release film 江苏斯迪克新材料科技股份有限公司 2025-04-11 CN claimed
CN-119638965-A Polyester microparticles, process for producing the same, and injection-filled article 广东粤港澳大湾区黄埔材料研究院 2025-03-18 CN claimed
CN-118853722-B Method for improving yield of synthesized L-isoleucine based on methyl malic acid pathway and engineering strain 中国农业科学院北京畜牧兽医研究所 2024-12-06 CN claimed
CN-118638831-B Coli engineering strain with phage resistance for producing methyl malic acid, construction and fermentation production method 中国农业科学院北京畜牧兽医研究所 2024-10-29 CN claimed
CN-118853722-A Method for improving yield of synthesized L-isoleucine based on methyl malic acid pathway and engineering strain 中国农业科学院北京畜牧兽医研究所 2024-10-29 CN claimed
CN-118638831-A Coli engineering strain with phage resistance for producing methyl malic acid, construction and fermentation production method 中国农业科学院北京畜牧兽医研究所 2024-09-13 CN claimed
CN-118530442-A Polyester microparticle, preparation method thereof and soluble microneedle patch containing polyester microparticle 广东粤港澳大湾区黄埔材料研究院 2024-08-23 CN claimed
CN-117683802-B Ralstonia engineering strain for producing isoleucine through methyl malic acid pathway, construction method and production method thereof 中国农业科学院北京畜牧兽医研究所 2024-07-05 CN claimed
WO-2023081515-A1 BIODEGRADABLE SUSTAINABLE POLYESTERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-05-11 WO claimed
US-11229621-B2 Pharmaceutical compositions of dimethyl fumarate ARBOR PHARMACEUTICALS, LLC (US) 2022-01-25 US claimed
WO-2021136977-A1 A PROCESS FOR PRODUCING TRIMELLITIC ACID FROM BIOMASS INDIAN INSTITUTE OF TECHNOLOGY, DELHI (IN) 2021-07-08 WO claimed
WO-2021019555-A1 A PROCESS FOR THE PREPARATION OF 4-AMINO-2-HYDROXY-4-OXOBUTANOIC ACID AND PRODUCT PREPARED THEREFROM INDIAN COUNCIL OF MEDICAL RESEARCH (IN) 2021-02-04 WO claimed
US-20200155496-A1 Pharmaceutical Compositions of Dimethyl Fumarate HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT 2020-05-21 US claimed
US-20150056215-A1 METHODS OF TREATING PROLIFERATIVE DISORDERS WITH MALATE OR DERIVATIVES THEREOF BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2015-02-26 US claimed
WO-2014160633-A1 PHARMACEUTICAL COMPOSITIONS OF DIMETHYL FUMARATE XENOPORT, INC. (US) 2014-10-02 WO claimed
US-20140284245-A1 PHARMACEUTICAL COMPOSITIONS OF DIMETHYL FUMARATE XENOPORT, INC. (US) 2014-09-25 US claimed
CN-102276689-A Chemical synthesis method of histone deacetylase inhibitor FK228 and application thereof 2011-12-14 CN claimed
US-20070190187-A1 FORMULATION FOR ENHANCED DELIVERY OF PHENETHYLAMINE KNELLER BRUCE W 2007-08-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070190187-A1 FORMULATION FOR ENHANCED DELIVERY OF PHENETHYLAMINE MAOB, PNMT, MAOA SMN1; SMN2 1565/4885SLC22A6 855/4885KMT2A 96/4885
US-11229621-B2 Pharmaceutical compositions of dimethyl fumarate FH, SDHB, SDHA SMN1; SMN2 2659/4885SLC22A6 886/4885KMT2A 1144/4885
US-20200155496-A1 Pharmaceutical Compositions of Dimethyl Fumarate FH, SDHB, SDHA SMN1; SMN2 2659/4885SLC22A6 886/4885KMT2A 1144/4885
US-20150056215-A1 METHODS OF TREATING PROLIFERATIVE DISORDERS WITH MALATE OR DERIVATIVES THEREOF MDH2, MDH1, ME1 SMN1; SMN2 3163/4885SLC22A6 298/4885KMT2A 1013/4885
US-20140284245-A1 PHARMACEUTICAL COMPOSITIONS OF DIMETHYL FUMARATE FH, SDHB, SDHA SMN1; SMN2 2659/4885SLC22A6 886/4885KMT2A 1144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.