Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.42 |
| ▸ | FABP4 | P15090 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172383 | 0.83 | MAPT (0.53) | TACR1LMNAMAPTRXFP1TBXAS1 | |
| SCHEMBL7812479 | 0.77 | LMNA (0.51) | TACR1LMNATHRB | |
| SCHEMBL5859668 | 0.76 | SMN1; SMN2 (0.56) | FABP4ALDH1A1TBXA2RMAPTRXFP1 | |
| SCHEMBL30427737 | 0.74 | FFAR4 (0.52) | TACR1LMNAMAPTRXFP1THRB | |
| SCHEMBL5726321 | 0.73 | TACR1 (0.47) | TACR1 | |
| SCHEMBL1015795 | 0.71 | LMNA (0.54) | TACR1LMNATHRB | |
| SCHEMBL1471504 | 0.71 | NR1H4 (0.51) | FABP4ALDH1A1TBXA2RMEN1KMT2A | |
| SCHEMBL25138788 | 0.70 | TACR1 (0.46) | TACR1 | |
| SCHEMBL7150587 | 0.70 | MAPT (0.60) | MAPTRXFP1THRB | |
| SCHEMBL14334756 | 0.69 | POLB (0.54) | TACR1ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6998423-B2 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | PFIZER INC. (US) | 2006-02-14 | — | — | US | claimed |