Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.49 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18126611 | 0.84 | MAPT (0.66) | SMN1; SMN2KMT2AALDH1A1PLAAT3PLAAT5 | |
| SCHEMBL7829175 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AALDH1A1PLAAT3PLAAT5 | |
| SCHEMBL5859621 | 0.79 | AKR1C3 (0.43) | SMN1; SMN2KMT2AALDH1A1PLAAT3PLAAT5 | |
| SCHEMBL5024832 | 0.79 | SMN1; SMN2 (0.68) | SMN1; SMN2KMT2AALDH1A1PLAAT3PLAAT5 | |
| SCHEMBL5860827 | 0.76 | TACR1 (0.42) | KMT2AALDH1A1FABP4RXFP1MAPT | |
| SCHEMBL11850224 | 0.76 | PTGFR (0.57) | KMT2AALDH1A1FABP4TBXA2R | |
| Water SCHEMBL11730250 | 0.75 | PTGFR (0.56) | KMT2AALDH1A1FABP4TBXA2R | |
| SCHEMBL11037045 | 0.75 | PLAAT3 (0.58) | SMN1; SMN2KMT2AALDH1A1PLAAT3PLAAT5 | |
| SCHEMBL4946092 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2KMT2AALDH1A1PLAAT3PLAAT5 | |
| SCHEMBL5859766 | 0.75 | FABP4 (0.57) | ALDH1A1FABP4TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6998423-B2 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | PFIZER INC. (US) | 2006-02-14 | — | — | US | claimed |