Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.46 |
| ▸ | MCHR2 | Q969V1 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL521889 | 0.90 | GLS (0.52) | GLSHTR7ALDH1A1MEN1LMNA | |
| SCHEMBL2075325 | 0.90 | GLS (0.68) | GLSHTR7ALDH1A1MEN1LMNA | |
| SCHEMBL6069917 | 0.89 | GLS (0.67) | GLSHTR7ALDH1A1MEN1LMNA | |
| SCHEMBL29190623 | 0.81 | GLS (0.59) | GLSMEN1LMNAKMT2APKM | |
| SCHEMBL14923499 | 0.81 | GLS (0.59) | GLSMEN1LMNAKMT2ANPC1 | |
| SCHEMBL30833705 | 0.81 | GLS (0.59) | GLSMEN1LMNAKMT2APKM | |
| SCHEMBL22126712 | 0.81 | GLS (0.59) | GLSHTR7LMNACNR1CNR2 | |
| SCHEMBL16931087 | 0.80 | GLS (0.65) | GLSHTR7ALDH1A1MEN1LMNA | |
| SCHEMBL521026 | 0.80 | GLS (0.65) | GLSALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL22502262 | 0.79 | GLS (0.56) | GLSLMNACNR1CNR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101948433-B | Method for separating and purifying substituted indazole isomer | UNIV ZHENGZHOU | 2012-05-09 | — | — | CN | claimed |
| CN-101948433-B | Method for separating and purifying substituted indazole isomer | UNIV ZHENGZHOU | 2012-05-09 | — | — | CN | disclosed |
| CN-101948433-A | Method for separating and purifying substituted indazole isomers | UNIV ZHENGZHOU | 2011-01-19 | — | — | CN | disclosed |
| US-7071182-B2 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBOTT LABORATORIES (US) | 2006-07-04 | — | — | US | disclosed |
| US-7049307-B2 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBOTT LABORATORIES (US) | 2006-05-23 | — | — | US | disclosed |
| US-20050277638-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBVIE INC. | 2005-12-15 | — | — | US | disclosed |
| US-20050187279-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBVIE INC. | 2005-08-25 | — | — | US | disclosed |
| US-20050137187-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBOTT LABORATORIES | 2005-06-23 | — | — | US | disclosed |
| US-20050137243-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBOTT LABORATORIES | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137187-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | GLS 1607/4885HTR7 125/4885ALDH1A1 2303/4885 |
| US-20050137243-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | GLS 1607/4885HTR7 125/4885ALDH1A1 2303/4885 |
| US-20050277638-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | GLS 1607/4885HTR7 125/4885ALDH1A1 2303/4885 |
| US-20050187279-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | GLS 1607/4885HTR7 125/4885ALDH1A1 2303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.