Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL606119 | 0.78 | LMNA (0.44) | LMNACES2CES1MAPK1RIPK1 | |
| SCHEMBL5861661 | 0.76 | LMNA (0.42) | LMNACES2CES1MAPK1RIPK1 | |
| SCHEMBL5860193 | 0.75 | AOC3 (0.48) | LMNACES2CES1MAPK1RIPK1 | |
| SCHEMBL60356 | 0.74 | AOC3 (0.57) | LMNACES2CES1MAPK1RIPK1 | |
| SCHEMBL9683893 | 0.74 | AOC3 (0.57) | LMNACES2CES1MAPK1RIPK1 | |
| SCHEMBL11407130 | 0.72 | AOC3 (0.50) | LMNARIPK1AOC3POLBL3MBTL1 | |
| SCHEMBL7914378 | 0.72 | AOC3 (0.50) | LMNARIPK1AOC3POLBL3MBTL1 | |
| Propionic Acid SCHEMBL1082124 | 0.72 | AOC3 (0.46) | LMNACES2CES1MAPK1RIPK1 | |
| SCHEMBL11180172 | 0.71 | LMNA (0.50) | LMNACES2CES1MAPK1AOC3 | |
| SCHEMBL4976204 | 0.71 | AOC3 (0.48) | LMNACES2CES1MAPK1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060471-B2 | Stereoselective chemoenzymatic process for the preparation of optically enriched phenylglycidates as precursors of taxol side chain | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2006-06-13 | — | — | US | disclosed |