Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60356 | 1.00 | AOC3 (0.57) | AOC3LMNACES2CES1MAPK1 | |
| SCHEMBL5860575 | 0.85 | LMNA (0.48) | AOC3LMNACES2CES1MAPK1 | |
| SCHEMBL14632149 | 0.84 | AOC3 (0.55) | AOC3LMNACES2CES1MAPK1 | |
| SCHEMBL16654109 | 0.83 | AOC3 (0.48) | AOC3LMNACES2CES1MAPK1 | |
| SCHEMBL5860193 | 0.83 | AOC3 (0.48) | AOC3LMNACES2CES1MAPK1 | |
| SCHEMBL28369056 | 0.83 | AOC3 (0.48) | AOC3LMNACES2CES1MAPK1 | |
| SCHEMBL17093303 | 0.83 | AOC3 (0.48) | AOC3LMNACES2CES1MAPK1 | |
| SCHEMBL6874332 | 0.83 | AOC3 (0.48) | AOC3LMNACES2CES1MAPK1 | |
| SCHEMBL4976204 | 0.83 | AOC3 (0.48) | AOC3LMNACES2CES1MAPK1 | |
| SCHEMBL13543221 | 0.83 | AOC3 (0.53) | AOC3LMNACES2CES1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132457-A | Stereospecific synthesis of 2(R)-2-methyl-3-dimethylamino-propiophenone (d-DAMP) | MALLINCKRODT SPECIALTY CHEMICALS COMPANY (US) | 1992-07-21 | — | — | US | disclosed |