Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4972971 | 0.84 | KCNH2 (0.44) | KIF11KCNH2OPRM1OPRD1CHRM3 | |
| SCHEMBL4638235 | 0.83 | KIF11 (0.39) | KIF11KCNH2OPRM1OPRD1CHRM3 | |
| SCHEMBL5860456 | 0.76 | CYP2C19 (0.41) | KIF11KCNH2CYP2C19HIF1ACYP1A2 | |
| SCHEMBL5861491 | 0.72 | KIF11 (0.43) | KIF11KCNH2OPRM1OPRD1MRGPRX2 | |
| SCHEMBL10234508 | 0.72 | CYP2C19 (0.46) | KIF11KCNH2OPRM1CHRM3CYP2C19 | |
| SCHEMBL489171 | 0.71 | CNR1 (0.35) | KCNH2OPRM1OPRD1CHRM3MRGPRX2 | |
| SCHEMBL18408916 | 0.70 | CYP2C19 (0.48) | KCNH2CHRM3CYP2C19HIF1ACYP1A2 | |
| SCHEMBL5571854 | 0.70 | CYP2C19 (0.48) | KCNH2CHRM3CYP2C19HIF1ACYP1A2 | |
| SCHEMBL16714035 | 0.69 | CYP2C19 (0.45) | CYP2C19HIF1ACYP1A2CYP2D6KCNN4 | |
| SCHEMBL607430 | 0.69 | CYP2C19 (0.45) | CYP2C19HIF1ACYP1A2CYP2D6KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060471-B2 | Stereoselective chemoenzymatic process for the preparation of optically enriched phenylglycidates as precursors of taxol side chain | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2006-06-13 | — | — | US | disclosed |