SCHEMBL5861735

SCHEMBL5861735

CCCCCCOc1ccc(C(C)(C)C)cc1S(=O)(=O)C(=[N+]=[N-])C(=O)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRA P10827 2/20 0.40
THRB P10828 2/20 0.40
S1PR3 Q99500 1/20 0.40
TRPV1 Q8NER1 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
ESR1 P03372 2/20 0.38
ALDH1A1 P00352 3/20 0.37
HSD17B10 Q99714 1/20 0.37
NR1I2 O75469 2/20 0.36
HPGD P15428 1/20 0.36
POLB P06746 1/20 0.36
PLA2G2D Q9UNK4 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5862532 0.99 SMN1; SMN2 (0.39) THRATHRBS1PR3TRPV1SMN1; SMN2
SCHEMBL5861740 0.96 ALDH1A1 (0.38) TRPV1SMN1; SMN2KDM4EGAAESR1
SCHEMBL5861721 0.88 S1PR3 (0.41) THRATHRBS1PR3KDM4EGAA
SCHEMBL5861716 0.87 POLB (0.40) THRATHRBS1PR3SMN1; SMN2KDM4E
SCHEMBL5862965 0.86 PTPN11 (0.41) THRATHRBS1PR3SMN1; SMN2KDM4E
SCHEMBL5862968 0.85 ESR1 (0.41) THRATHRBS1PR3TRPV1SMN1; SMN2
SCHEMBL5861729 0.85 ESR1 (0.41) THRATHRBS1PR3TRPV1SMN1; SMN2
SCHEMBL5861568 0.85 ESR1 (0.41) THRATHRBS1PR3TRPV1SMN1; SMN2
SCHEMBL5862347 0.85 ESR1 (0.41) THRATHRBS1PR3TRPV1SMN1; SMN2
SCHEMBL5862942 0.85 PTPN11 (0.39) THRATHRBS1PR3SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7109311-B2 Sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-09-19 US disclosed
US-20040167322-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167322-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process POLL, VEGFA, PIM3 THRA 2769/4885THRB 3554/4885S1PR3 2134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.