Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Aminobenzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | TPMT | P51580 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminobenzoic Acid SCHEMBL29696239 | 0.95 | TSHR (0.63) | TSHRTP53SRD5A2CA1CA2 | |
| Aminobenzoic Acid SCHEMBL8249 | 0.95 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL7648718 | 0.95 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Aminobenzoic Acid SCHEMBL1768920 | 0.95 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL9717815 | 0.95 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Aminobenzoic Acid SCHEMBL25326411 | 0.92 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Aminobenzoic Acid SCHEMBL10995559 | 0.92 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Aminobenzoic Acid SCHEMBL11038536 | 0.92 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Aminobenzoic Acid SCHEMBL25354995 | 0.92 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Aminobenzoic Acid SCHEMBL20549750 | 0.92 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7008646-B2 | Cubic liquid crystalline compositions and methods for their preparation | CHILDREN'S HOSPITAL RESEARCH FOUNDATION | 2006-03-07 | — | — | US | claimed |
| EP-1361865-A2 | CUBIC LIQUID CRYSTALLINE COMPOSITIONS AND METHODS FOR THEIR PREPARATION | THE PROCTER & GAMBLE COMPANY (US) | 2003-11-19 | — | — | EP | claimed |
| US-20020160040-A1 | Cubic liquid crystalline compositions and methods for their preparation | CHILDREN'S HOSPITAL RESEARCH FOUNDATION | 2002-10-31 | — | — | US | claimed |
| WO-2002066014-A2 | CUBIC LIQUID CRYSTALLINE COMPOSITIONS AND METHODS FOR THEIR PREPARATION | THE PROCTER & GAMBLE COMPANY (US) | 2002-08-29 | — | — | WO | claimed |
| CN-107011924-A | Light alignment materials with side draw generation | 罗利克有限公司 | 2017-08-04 | — | — | CN | disclosed |
| CN-106873249-A | Light alignment materials with side draw generation | 罗利克有限公司 | 2017-06-20 | — | — | CN | disclosed |
| US-7008646-B2 | Cubic liquid crystalline compositions and methods for their preparation | CHILDREN'S HOSPITAL RESEARCH FOUNDATION | 2006-03-07 | — | — | US | disclosed |
| CN-1638735-A | Cubic liquid crystalline compositions and methods for their preparation | CHILDRENS HOSP MEDICAL CENTER (US) | 2005-07-13 | — | — | CN | disclosed |
| EP-1361865-A2 | CUBIC LIQUID CRYSTALLINE COMPOSITIONS AND METHODS FOR THEIR PREPARATION | THE PROCTER & GAMBLE COMPANY (US) | 2003-11-19 | — | — | EP | disclosed |
| US-20020160040-A1 | Cubic liquid crystalline compositions and methods for their preparation | CHILDREN'S HOSPITAL RESEARCH FOUNDATION | 2002-10-31 | — | — | US | disclosed |
| WO-2002066014-A2 | CUBIC LIQUID CRYSTALLINE COMPOSITIONS AND METHODS FOR THEIR PREPARATION | THE PROCTER & GAMBLE COMPANY (US) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020160040-A1 | Cubic liquid crystalline compositions and methods for their preparation | SKP1, CCNB1, CRYAA | TSHR 4568/4885TP53 1409/4885SRD5A2 2576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.