Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL8468675 | 1.00 | NAAA (0.65) | NAAASIGMAR1CES2CES1EPHX1 | |
| Benzoic Acid SCHEMBL32671576 | 1.00 | NAAA (0.65) | NAAASIGMAR1CES2CES1EPHX1 | |
| Benzoic Acid SCHEMBL5862551 | 0.93 | NAAA (0.54) | NAAASIGMAR1CES2CES1HTT | |
| Benzoic Acid SCHEMBL31357355 | 0.92 | NAAA (0.56) | NAAASIGMAR1CES2CES1EPHX1 | |
| Dodecane SCHEMBL29930922 | 0.89 | TSHR (0.64) | NAAACES2CES1ALDH1A1TSHR | |
| Benzoic Acid SCHEMBL9089056 | 0.89 | TSHR (0.64) | NAAACES2CES1ALDH1A1TSHR | |
| Undecane SCHEMBL15129102 | 0.89 | TSHR (0.64) | NAAACES2CES1ALDH1A1TSHR | |
| Benzoic Acid SCHEMBL8371517 | 0.89 | TSHR (0.64) | NAAACES2CES1ALDH1A1TSHR | |
| Dodecane SCHEMBL28594534 | 0.89 | TSHR (0.64) | NAAACES2CES1ALDH1A1TSHR | |
| Hexadecane SCHEMBL28733004 | 0.89 | TSHR (0.64) | NAAACES2CES1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423818-B | Modified asphalt and preparation method thereof | 广州大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-111423818-A | Modified asphalt and preparation method thereof | 广州大学 | 2020-07-17 | — | — | CN | disclosed |
| US-7094516-B2 | Benzobisazole compound and optical recording medium containing the compound | MITSUI CHEMICALS, INC. (JP) | 2006-08-22 | — | — | US | disclosed |
| US-20030091931-A1 | Benzbisazole compound and optical recording medium containing the compound | MITSUI CHEMICALS, INC. (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-1245571-A1 | BENZBISAZOLE COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING THE COMPOUND | Mitsui Chemicals, Inc. (JP) | 2002-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030091931-A1 | Benzbisazole compound and optical recording medium containing the compound | DAO, CACNA1I, KCNB2 | NAAA 936/4885SIGMAR1 1304/4885CES2 1387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.