SCHEMBL586358

SCHEMBL586358

CCCCc1ccccc1C(O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 9/20 0.48
CYSLTR1 Q9Y271 9/20 0.48
CYP2C9 P11712 2/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
LIPG Q9Y5X9 1/20 0.42
LMNA P02545 1/20 0.41
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
NAAA Q02083 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6939638 0.84 MEN1 (0.41) CYSLTR2CYSLTR1CYP2C9MEN1MAPT
SCHEMBL12506235 0.82 CYSLTR2 (0.47) CYSLTR2CYSLTR1CYP2C9LIPGLMNA
SCHEMBL6899385 0.82 MEN1 (0.49) CYP2C9MEN1MAPTKMT2ALMNA
SCHEMBL6547601 0.81 CYSLTR2 (0.46) CYSLTR2CYSLTR1CYP2C9LIPGCYP3A4
Hydrogen Peroxide SCHEMBL2318664 0.80 CYSLTR2 (0.51) CYSLTR2CYSLTR1CYP2C9LIPGCYP3A4
SCHEMBL16155004 0.80 CYSLTR2 (0.48) CYSLTR2CYSLTR1CYP2C9LIPGCYP3A4
SCHEMBL5932304 0.80 CYSLTR2 (0.48) CYSLTR2CYSLTR1CYP2C9LIPGCYP3A4
SCHEMBL19512046 0.79 CYSLTR2 (0.47) CYSLTR2CYSLTR1CYP2C9LIPGLMNA
SCHEMBL19511633 0.77 CYSLTR2 (0.49) CYSLTR2CYSLTR1CYP2C9LIPGCYP3A4
SCHEMBL11394818 0.77 CYSLTR2 (0.46) CYSLTR2CYSLTR1CYP2C9LIPGCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957467-B2 Coated overhead conductor GENERAL CABLE TECHNOLOGIES CORPORATION (US) 2021-03-23 US disclosed
US-10818409-B2 Cables with improved coverings and methods of forming thereof GENERAL CABLE TECHNOLOGIES CORPORATION (US) 2020-10-27 US disclosed
US-20180218805-A1 CABLES WITH IMPROVED COVERINGS AND METHODS OF FORMING THEREOF GENERAL CABLE TECHNOLOGIES CORPORATION 2018-08-02 US disclosed
EP-2941776-B1 FIRE AND WATER RESISTANT CABLE COVER GEN CABLE TECHNOLOGIES CORP (US) 2018-02-21 EP disclosed
EP-2973609-B1 FIRE AND WATER RESISTANT CABLE GENERAL CABLE TECH CORP (US) 2017-11-01 EP disclosed
US-9777206-B2 Thermally conductive compositions and cables thereof GENERAL CABLE TECHNOLOGIES CORPORATION (US) 2017-10-03 US disclosed
EP-3103123-A1 METHODS OF FORMING CABLES WITH IMPROVED COVERINGS General Cable Technologies Corporation (US) 2016-12-14 EP disclosed
EP-3092654-A1 COATED OVERHEAD CONDUCTOR General Cable Technologies Corporation (US) 2016-11-16 EP disclosed
EP-2973609-A1 FIRE AND WATER RESISTANT CABLE General Cable Technologies Corporation (US) 2016-01-20 EP disclosed
EP-2941776-A1 FIRE AND WATER RESISTANT CABLE COVER General Cable Technologies Corporation (US) 2015-11-11 EP disclosed
EP-2702100-A2 INSULATION COMPOSITIONS General Cable Technologies Corporation (US) 2014-03-05 EP disclosed
US-20130269976-A1 LEAD-FREE CABLE CONTAINING BISMUTH COMPOUND GENERAL CABLE TECHNOLOGIES CORPORATION (US) 2013-10-17 US disclosed
EP-2582751-A2 INSULATION CONTAINING STYRENE COPOLYMERS General Cable Technologies Corporation (US) 2013-04-24 EP disclosed
WO-2013023118-A1 LEAD-FREE CABLE CONTAINING BISMUTH COMPOUND GENERAL CABLE TECHNOLOGIES CORPORATION (US) 2013-02-14 WO disclosed
WO-2012149372-A2 INSULATION COMPOSITIONS GENERAL CABLE TECHNOLOGIES CORPORATION (US) 2012-11-01 WO disclosed
EP-2418255-A1 Polymer compositions and their use as cable coverings General Cable Technologies Corporation (US) 2012-02-15 EP disclosed
WO-2011159611-A2 INSULATION CONTAINING STYRENE COPOLYMERS GENERAL CABLE TECHNOLOGIES CORPORATION (US) 2011-12-22 WO disclosed
US-20100022683-A1 HARD GRADE EPR INSULATION COMPOSITIONS GENERAL CABLE TECHNOLOGIES CORPORATION (US) 2010-01-28 US disclosed
US-7572927-B2 Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound FUJIFILM CORPORATION (JP) 2009-08-11 US disclosed
US-20080194816-A1 Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194816-A1 Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound DDT, OXER1, OSTC CYSLTR2 2795/4885CYSLTR1 2903/4885CYP2C9 1386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.