SCHEMBL6899385

SCHEMBL6899385

CCc1ccccc1C(O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.49
MAPT P10636 1/20 0.49
CYP2C9 P11712 1/20 0.49
KMT2A Q03164 1/20 0.49
LMNA P02545 4/20 0.47
OPRM1 P35372 1/20 0.46
OPRD1 P41143 1/20 0.46
OPRK1 P41145 1/20 0.46
OPRL1 P41146 1/20 0.46
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SLC6A2 P23975 2/20 0.43
SLC6A4 P31645 2/20 0.43
SLC6A3 Q01959 2/20 0.43
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
KCNH2 Q12809 1/20 0.42
POLB P06746 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30910943 0.85 ALDH1A1 (0.42) MEN1MAPTCYP2C9KMT2ALMNA
SCHEMBL21831295 0.85 ALDH1A1 (0.42) MEN1MAPTCYP2C9KMT2ALMNA
SCHEMBL27560047 0.84 MEN1 (0.44) MEN1MAPTCYP2C9KMT2ALMNA
SCHEMBL11604430 0.84 SLC6A2 (0.49) MEN1CYP2C9KMT2ALMNAOPRM1
SCHEMBL6444765 0.82 MEN1 (0.46) MEN1MAPTCYP2C9KMT2ALMNA
SCHEMBL30307843 0.82 MEN1 (0.46) MEN1MAPTCYP2C9KMT2ALMNA
SCHEMBL11602112 0.81 CYP3A4 (0.51) MAPTLMNAOPRM1OPRD1OPRK1
SCHEMBL13454472 0.80 TYR (0.47) MEN1MAPTCYP2C9KMT2ALMNA
SCHEMBL8183495 0.80 MEN1 (0.44) MEN1MAPTCYP2C9KMT2ALMNA
SCHEMBL28200881 0.79 MAPT (0.45) MEN1MAPTCYP2C9KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023106973-A1 NOVEL HEPATOPROTECTIVE AGENTS ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ВАЛЕНТА-ИНТЕЛЛЕКТ" 2023-06-15 WO disclosed
US-7683203-B2 Polymerizable compound and composition containing the polymerizable compound ADEKA CORPORATION (JP) 2010-03-23 US disclosed
EP-1385856-A2 AMINO ACID COMPLEXES OF C-ARYL GLUCOSIDES FOR TREATMENT OF DIABETES AND METHOD Bristol-Myers Squibb Company (US) 2004-02-04 EP disclosed
WO-2002083066-A2 AMINO ACID COMPLEXES OF C-ARYL GLUCOSIDES FOR TREATMENT OF DIABETES AND METHOD BRISTOL-MYERS SQUIBB COMPANY (US) 2002-10-24 WO disclosed
EP-1224195-A1 C-ARYL GLUCOSIDE SGLT2 INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2002-07-24 EP disclosed
WO-2001027128-A1 C-ARYL GLUCOSIDE SGLT2 INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2001-04-19 WO disclosed