SCHEMBL586400

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2676756	0.96	SSTR4 (0.39)	SSTR4GPR119TP53JAK2JAK1
	SCHEMBL590425	0.89	SLC6A2 (0.41)	SSTR4GPR119TP53ALDH1A1MEN1
	SCHEMBL10090874	0.89	SLC6A2 (0.41)	SSTR4GPR119TP53ALDH1A1MEN1
	SCHEMBL10090902	0.86	SSTR4 (0.37)	SSTR4GPR119
	SCHEMBL2675147	0.83	SSTR4 (0.41)	SSTR4GPR119TP53ALDH1A1PDE4D
	SCHEMBL26180110	0.77	PIK3CD (0.48)	SSTR4GPR119PDE4DPDE4B
	SCHEMBL590981	0.77	SLC6A2 (0.55)	GPR119ALDH1A1PDE4DPDE4B
	SCHEMBL592676	0.76	GPR119 (0.41)	GPR119ALDH1A1MEN1KMT2ANPSR1
	SCHEMBL586621	0.76	SLC6A2 (0.45)	GPR119NPSR1MAPT
	SCHEMBL10090887	0.75	SLC6A2 (0.40)	SSTR4GPR119MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.