Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27852723 | 0.89 | RECQL (0.74) | RECQLALDH1A1LMNAGAAKDM4E | |
| SCHEMBL402509 | 0.88 | ALDH1A1 (0.57) | RECQLALDH1A1LMNAGAAKDM4E | |
| SCHEMBL28731742 | 0.85 | POLB (0.65) | RECQLALDH1A1LMNAGAAKDM4E | |
| SCHEMBL21360416 | 0.84 | ALDH1A1 (0.61) | RECQLALDH1A1LMNAGAAKDM4E | |
| SCHEMBL15160744 | 0.83 | RECQL (0.68) | RECQLALDH1A1LMNAGAAKDM4E | |
| SCHEMBL22069657 | 0.82 | RECQL (1.00) | RECQLALDH1A1LMNAGAAKDM4E | |
| SCHEMBL401828 | 0.82 | RECQL (0.66) | RECQLALDH1A1LMNAGAAKDM4E | |
| SCHEMBL7361077 | 0.81 | RECQL (0.65) | RECQLALDH1A1LMNAGAAKDM4E | |
| SCHEMBL15160754 | 0.81 | RECQL (0.64) | RECQLALDH1A1LMNAGAAKDM4E | |
| SCHEMBL18361685 | 0.80 | CA1 (0.71) | ALDH1A1LMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984642-B1 | Substituted phenylcyclohexane carboxylic acid amides and their use as adenosine uptake inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 2006-01-10 | — | — | US | disclosed |
| EP-1187812-B1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THEIR USE AS ADENOSINE UPTAKE INHIBITORS | BAYER HEALTHCARE AG (DE) | 2005-09-07 | — | — | EP | disclosed |
| EP-1187812-A2 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THEIR USE AS ADENOSINE UPTAKE INHIBITORS | Bayer Aktiengesellschaft (DE) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000073274-A2 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THEIR USE AS ADENOSINE UPTAKE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-07 | — | — | WO | disclosed |