Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.41 |
| ▸ | HRH1 | P35367 | 5/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5864422 | 0.94 | POLB (0.46) | GAALMNAMAPTPOLBRAB9A | |
| SCHEMBL5864345 | 0.92 | POLB (0.44) | GAALMNAMAPTPOLBRAB9A | |
| SCHEMBL5864471 | 0.87 | GAA (0.46) | GAAPOLBRAB9ATP53MCHR1 | |
| SCHEMBL5864499 | 0.87 | POLB (0.45) | MAPTPOLBSMN1; SMN2 | |
| SCHEMBL5864419 | 0.81 | POLB (0.44) | GAALMNAPOLBRAB9ATP53 | |
| SCHEMBL5864750 | 0.80 | ALDH1A1 (0.40) | POLBTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL5864337 | 0.80 | POLB (0.43) | GAAPOLBRAB9ATP53CYP2D6 | |
| SCHEMBL5864465 | 0.79 | PDE6D (0.44) | GAACYP2D6HRH1CHRM1KCNH2 | |
| Hydrochloric Acid SCHEMBL6777163 | 0.78 | PDE6D (0.44) | GAAMAPTCYP2D6HRH1CHRM1 | |
| SCHEMBL5864495 | 0.74 | HTT (0.40) | LMNAPOLBRAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984642-B1 | Substituted phenylcyclohexane carboxylic acid amides and their use as adenosine uptake inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 2006-01-10 | — | — | US | disclosed |