Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5864484 | 0.86 | HSP90AB1 (0.50) | HSP90AB1HSP90AA1POLB | |
| SCHEMBL6307209 | 0.81 | HSP90AB1 (0.54) | HSP90AB1HSP90AA1MAPTKDM4ENPC1 | |
| SCHEMBL9350626 | 0.79 | HSP90AB1 (0.52) | HSP90AB1HSP90AA1POLB | |
| SCHEMBL5864575 | 0.78 | HSP90AB1 (0.50) | HSP90AB1HSP90AA1POLB | |
| SCHEMBL24228122 | 0.77 | TSHR (0.43) | HSP90AB1HSP90AA1TSHRLMNAMAPT | |
| SCHEMBL6003419 | 0.77 | TSHR (0.43) | HSP90AB1HSP90AA1TSHRLMNAMAPT | |
| SCHEMBL8071682 | 0.77 | HSP90AB1 (0.71) | HSP90AB1HSP90AA1POLB | |
| SCHEMBL3631158 | 0.77 | HSP90AB1 (0.71) | HSP90AB1HSP90AA1LMNAMAPTKDM4E | |
| SCHEMBL23523689 | 0.75 | HSP90AB1 (0.47) | HSP90AB1HSP90AA1HSD17B10POLB | |
| SCHEMBL9199934 | 0.72 | HSP90AB1 (0.48) | HSP90AB1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5262749-A | — | — | None | — | — | JP | disclosed |
| US-7002011-B1 | Process for the preparation of 2-amino-4-chloro-1,3,5-triazines | AVENTIS CROPSCIENCE GMBH (DE) | 2006-02-21 | — | — | US | disclosed |
| EP-1097146-A1 | METHOD FOR PRODUCING 2-AMINO-4-CHLORO-1, 3, 5-TRIAZINES | Aventis CropScience GmbH (DE) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002868-A1 | METHOD FOR PRODUCING 2-AMINO-4-CHLORO-1, 3, 5-TRIAZINES | AVENTIS CROPSCIENCE GMBH (DE) | 2000-01-20 | — | — | WO | disclosed |
| EP-0545149-B1 | Process for the preparation of 6-trifluoromethyl-1,3,5-triazine derivatives | BASF AG (DE) | 1994-09-07 | — | — | EP | disclosed |
| JP-H05262749-A | PRODUCTION OF 6-TRIFLUOROMETHYL-1,3,5 TRIAZINE | BASF AG | 1993-10-12 | — | — | JP | disclosed |
| EP-0545149-A1 | Process for the preparation of 6-trifluoromethyl-1,3,5-triazine derivatives | BASF Aktiengesellschaft (DE) | 1993-06-09 | — | — | EP | disclosed |