SCHEMBL5864484

SCHEMBL5864484

CSc1nc(N)nc(C(C)(C)F)n1

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSP90AB1 P08238 2/20 0.50
HSP90AA1 P07900 6/20 0.41
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5864553 0.86 HSP90AB1 (0.52) HSP90AB1HSP90AA1POLB
SCHEMBL6307209 0.83 HSP90AB1 (0.54) HSP90AB1HSP90AA1POLB
SCHEMBL23242194 0.80 HSP90AA1 (0.37) HSP90AB1HSP90AA1
SCHEMBL5864575 0.80 HSP90AB1 (0.50) HSP90AB1HSP90AA1POLB
SCHEMBL9350626 0.78 HSP90AB1 (0.52) HSP90AB1HSP90AA1POLB
SCHEMBL23523689 0.77 HSP90AB1 (0.47) HSP90AB1HSP90AA1POLB
SCHEMBL8071682 0.75 HSP90AB1 (0.71) HSP90AB1HSP90AA1POLB
SCHEMBL3631158 0.75 HSP90AB1 (0.71) HSP90AB1HSP90AA1POLB
SCHEMBL5864462 0.71 HSP90AA1 (0.33) HSP90AB1HSP90AA1
SCHEMBL9199934 0.71 HSP90AB1 (0.48) HSP90AB1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10479777-B2 Herbicidal azines BASF SE (DE) 2019-11-19 US disclosed
US-10479777-B2 Herbicidal azines BASF SE (DE) 2019-11-19 US disclosed
US-9999222-B2 Herbicidal combination comprising azines BASF SE (DE) 2018-06-19 US disclosed
US-9999222-B2 Herbicidal combination comprising azines BASF SE (DE) 2018-06-19 US disclosed
US-9999222-B2 Herbicidal combination comprising azines BASF SE (DE) 2018-06-19 US disclosed
EP-3022191-B1 HERBICIDAL AZINES BASF SE (DE) 2017-03-01 EP disclosed
EP-3133920-A1 HERBICIDAL COMBINATION COMPRISING AZINES BASF SE (DE) 2017-03-01 EP disclosed
EP-3022191-B1 HERBICIDAL AZINES BASF SE (DE) 2017-03-01 EP disclosed
US-20170042154-A1 HERBICIDAL COMBINATION COMPRISING AZINES BASF SE (DE) 2017-02-16 US disclosed
US-20170042154-A1 HERBICIDAL COMBINATION COMPRISING AZINES BASF SE (DE) 2017-02-16 US disclosed
WO-2015162164-A1 HERBICIDAL COMBINATION COMPRISING AZINES BASF SE (DE) 2015-10-29 WO disclosed
US-20150289510-A1 HERBICIDAL AZINES BASF SE (DE) 2015-10-15 US disclosed
US-20150289510-A1 HERBICIDAL AZINES BASF SE (DE) 2015-10-15 US disclosed
US-20150289510-A1 HERBICIDAL AZINES BASF SE (DE) 2015-10-15 US disclosed
EP-2912024-A1 HERBICIDAL AZINES BASF SE (DE) 2015-09-02 EP disclosed
WO-2015007711-A1 HERBICIDAL AZINES BASF SE (DE) 2015-01-22 WO disclosed
WO-2014064094-A1 HERBICIDAL AZINES BASF SE (DE) 2014-05-01 WO disclosed
US-7002011-B1 Process for the preparation of 2-amino-4-chloro-1,3,5-triazines AVENTIS CROPSCIENCE GMBH (DE) 2006-02-21 US disclosed
EP-1097146-A1 METHOD FOR PRODUCING 2-AMINO-4-CHLORO-1, 3, 5-TRIAZINES Aventis CropScience GmbH (DE) 2001-05-09 EP disclosed
WO-2000002868-A1 METHOD FOR PRODUCING 2-AMINO-4-CHLORO-1, 3, 5-TRIAZINES AVENTIS CROPSCIENCE GMBH (DE) 2000-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10479777-B2 Herbicidal azines DDT, QDPR, HDHD5 HSP90AB1 1874/4885HSP90AA1 1788/4885POLB 3584/4885
US-20170042154-A1 HERBICIDAL COMBINATION COMPRISING AZINES CBR3, CBR1, DDT HSP90AB1 1777/4885HSP90AA1 1399/4885POLB 4485/4885
US-20150289510-A1 HERBICIDAL AZINES AZI2, DDT, CYP1A2 HSP90AB1 475/4885HSP90AA1 417/4885POLB 3427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.