Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.71 |
| ▸ | HSP90AA1 | P07900 | 9/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3631158 | 0.94 | HSP90AB1 (0.71) | HSP90AB1HSP90AA1ABCB1ADORA2AADORA1 | |
| SCHEMBL18062212 | 0.85 | HSP90AA1 (0.58) | HSP90AB1HSP90AA1ABCB1ADORA2AADORA1 | |
| SCHEMBL10876554 | 0.84 | HSP90AB1 (1.00) | HSP90AB1HSP90AA1ABCB1ADORA2AADORA1 | |
| SCHEMBL10971273 | 0.83 | HSP90AA1 (0.64) | HSP90AB1HSP90AA1ABCB1ADORA2AADORA1 | |
| SCHEMBL7537282 | 0.83 | HSP90AB1 (0.48) | HSP90AB1HSP90AA1ABCB1 | |
| SCHEMBL14020366 | 0.82 | HSP90AB1 (0.58) | HSP90AB1HSP90AA1ABCB1ADORA2AADORA1 | |
| SCHEMBL1710312 | 0.80 | HSP90AB1 (0.56) | HSP90AB1HSP90AA1ABCB1ADORA2AADORA1 | |
| SCHEMBL10916421 | 0.78 | HSP90AA1 (0.61) | HSP90AB1HSP90AA1ADORA2AADORA1 | |
| SCHEMBL6309389 | 0.78 | HSP90AB1 (0.54) | HSP90AB1HSP90AA1ABCB1ADORA2AADORA1 | |
| SCHEMBL6307209 | 0.78 | HSP90AB1 (0.54) | HSP90AB1HSP90AA1ABCB1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648755-B1 | Improved process for the preparation of 2,4-di(alkylamino)-6-alkylthio-s-triazines and 2-alkylamino-4,6-di(alkylthio)-s-triazines | CIBA SC HOLDING AG (CH) | 2000-08-02 | — | — | EP | disclosed |
| US-5420274-A | Process for the preparation of 2,4-di(alkylamino)-6-alkylthio-s-triazines | CIBA-GEIGY CORPORATION (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0648755-A1 | Improved process for the preparation of 2,4-Di(alkylamino)-6-alkylthio-s-triazines | CIBA-GEIGY AG (CH) | 1995-04-19 | — | — | EP | disclosed |
| EP-0174574-A2 | Fungicidal agents on the basis of triazine derivatives | BAYER AG (DE) | 1986-03-19 | — | — | EP | disclosed |