Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | QDPR | P09417 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5865291 | 0.88 | PDE4B (0.46) | RORCPDE4BEPHX2HRH1CCR3 | |
| SCHEMBL31202927 | 0.85 | IKBKB (0.47) | IKBKBPDE4BCHUKHRH1CCR3 | |
| Hydrochloric Acid SCHEMBL9013901 | 0.84 | IKBKB (0.46) | IKBKBPDE4BCHUKHRH1CCR3 | |
| SCHEMBL2749734 | 0.84 | PDE4B (0.53) | PDE4B | |
| SCHEMBL27088055 | 0.84 | F10 (0.51) | IKBKBPDE4BEPHX2MEN1KMT2A | |
| SCHEMBL3973906 | 0.82 | KDM4E (0.49) | RORCEGFR | |
| SCHEMBL5864915 | 0.80 | ALDH1A1 (0.49) | RORCIKBKBMEN1KMT2ARAB9A | |
| SCHEMBL21764928 | 0.80 | IKBKB (0.47) | RORCIKBKBPDE4BCHUKHRH1 | |
| SCHEMBL25769675 | 0.80 | CSNK2A1 (0.54) | RORC | |
| SCHEMBL5864867 | 0.79 | RORC (0.45) | RORCHRH1CCR3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030138-B2 | Benzamidine derivatives | SANKYO COMPANY, LIMITED (JP) | 2006-04-18 | — | — | US | disclosed |
| US-20040147555-A1 | Benzamidine derivatives | SANKYO COMPANY, LIMITED (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1375482-A1 | BENZAMIDINE DERIVATIVE | Sankyo Company, Limited (JP) | 2004-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147555-A1 | Benzamidine derivatives | F9, F7, F2 | RORC 4836/4885IKBKB 496/4885PDE4B 3861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.