Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201440 | 0.89 | PTGS2 (0.49) | PTGS2PTGS1TSHRCYP2C9PDPK1 | |
| SCHEMBL5865600 | 0.89 | PTGS2 (0.43) | PTGS2PTGS1LMNAALOX5MAPK14 | |
| SCHEMBL5865561 | 0.89 | PTGS1 (0.42) | PTGS2PTGS1SMN1; SMN2L3MBTL1 | |
| SCHEMBL5865655 | 0.88 | PTGS2 (0.42) | PTGS2PTGS1PDPK1MAPK14GABRP | |
| SCHEMBL5278633 | 0.88 | MAPK13 (0.46) | PTGS2PTGS1ALOX5MAPK14 | |
| SCHEMBL6885231 | 0.87 | PTGS2 (0.58) | PTGS2PTGS1TSHRCYP2C9CYP3A4 | |
| SCHEMBL5204715 | 0.87 | PTGS2 (0.58) | PTGS2PTGS1TSHRCYP2C9CYP3A4 | |
| SCHEMBL5865582 | 0.86 | PDPK1 (0.41) | PTGS2PTGS1PDPK1GABRPGABRD | |
| SCHEMBL5207906 | 0.84 | PTGS2 (0.49) | PTGS2PTGS1LMNANPC1MAPK1 | |
| SCHEMBL4674384 | 0.83 | PTGS2 (0.42) | PTGS2PTGS1RAB9ACYP2C9PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019144-B2 | 1,2,4-Triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CJ CORP. (KR) | 2006-03-28 | — | — | US | disclosed |
| US-20050075507-A1 | 1,2,4-Triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CJ CHEILJEDANG CORPORATION (KR) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075507-A1 | 1,2,4-Triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CYP4B1, CYP3A5, CYP7A1 | PTGS2 1769/4885PTGS1 523/4885RECQL 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.