⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18974042 | 1.00 | — | — | |
| SCHEMBL20510006 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL1412124 | 0.72 | — | — | |
| SCHEMBL16186777 | 0.72 | TSHR (0.37) | — | |
| SCHEMBL23985 | 0.71 | — | — | |
| SCHEMBL13616194 | 0.71 | — | — | |
| SCHEMBL20648 | 0.69 | — | — | |
| SCHEMBL13611580 | 0.69 | — | — | |
| SCHEMBL16668528 | 0.69 | — | — | |
| SCHEMBL135673 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032669-B | Orthoester compositions for affinity purification of oligonucleotides | 安捷伦科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-20230322742-A1 | ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES | AGILENT TECHNOLOGIES, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20230122968-A1 | ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES | AGILENT TECHNOLOGIES, INC. | 2023-04-20 | — | — | US | disclosed |
| US-11548876-B2 | Orthoester compositions for affinity purification of oligonucleotides | AGILENT TECHNOLOGIES, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-11299483-B2 | Orthoester compositions for affinity purification of oligonucleotides | AGILENT TECHNOLOGIES, INC. (US) | 2022-04-12 | — | — | US | disclosed |
| US-20200190129-A1 | ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES | AGILENT TECHNOLOGIES, INC. | 2020-06-18 | — | — | US | disclosed |
| US-20200181124-A1 | ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES | AGILENT TECHNOLOGIES, INC. | 2020-06-11 | — | — | US | disclosed |
| CN-103044345-A | Synthetic method of 1-(2-ethoxyl)-5-sulfydryl-1H-tetrazole | SHANXI XINTIANYUAN PHARM & CHEM CO LTD | 2013-04-17 | — | — | CN | disclosed |
| US-7776582-B2 | for gas chromatography; identifying an optically enhanced chiral ionic liquid (OCIL) for enantiomeric resolution | SIGMA-ALDRICH CO. (US) | 2010-08-17 | — | — | US | disclosed |
| WO-2009071524-A2 | INDOLINONE DERIVATIVES AND PROCESS FOR THEIR MANUFACTURE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009071523-A1 | PROCESS FOR THE MANUFACTURE OF AN INDOLINONE DERIVATIVE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-11 | — | — | WO | disclosed |
| US-20090145197-A1 | Optically Enhanced Chiral Ionic Liquids | SIGMA-ALDRICH CO. NEWCO INC. | 2009-06-11 | — | — | US | disclosed |
| US-7056925-B2 | for example, N-{2-[benzyl(2-hydroxyethyl)amino]-5-bromophenyl)}-N'-(5-cyano-2-pyrazinyl)urea, N-{5-bromo-2-[(2-hydroxy-2-phenylethyl)(methyl)amino]phenyl}-N'-(5-cyano-2-pyrazinyl)urea; anticarcinogenic agents | ABBOTT LABORATORIES (US) | 2006-06-06 | — | — | US | disclosed |
| EP-1534692-A1 | UREA DERIVATIVES AS KINASE INHIBITORS | Abbott Laboratories (US) | 2005-06-01 | — | — | EP | disclosed |
| US-20040259885-A1 | Urea kinase inhibitors | ABBVIE INC. | 2004-12-23 | — | — | US | disclosed |
| WO-2004014876-A1 | UREA DERIVATIVES AS KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2004-02-19 | — | — | WO | disclosed |
| US-20040034038-A1 | Urea kinase inhibitors | ABBOTT LABORATORIES | 2004-02-19 | — | — | US | disclosed |
| US-4410543-A | Carboxylated oxime-carbamates and their use in controlling pests | CIBA-GEIGY CORPORATION (US) | 1983-10-18 | — | — | US | disclosed |