Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399572 | 0.95 | S1PR1 (0.49) | L3MBTL1S1PR1RARARARBCYP1A2 | |
| SCHEMBL9483702 | 0.93 | L3MBTL1 (0.54) | L3MBTL1S1PR1KDM1AKDM4EMEN1 | |
| SCHEMBL9399442 | 0.93 | S1PR1 (0.51) | L3MBTL1S1PR1RARARARBCYP1A2 | |
| SCHEMBL9399556 | 0.90 | THRA (0.52) | L3MBTL1S1PR1RARARARBTHRA | |
| SCHEMBL9484097 | 0.90 | THRA (0.52) | L3MBTL1S1PR1RARARARBTHRA | |
| SCHEMBL9484969 | 0.89 | THRA (0.51) | L3MBTL1S1PR1RARARARBTDP1 | |
| SCHEMBL9484876 | 0.89 | L3MBTL1 (0.53) | L3MBTL1KDM1AKDM4EMEN1ALDH1A1 | |
| SCHEMBL16855921 | 0.88 | L3MBTL1 (0.45) | L3MBTL1S1PR1KDM1ARARARARB | |
| SCHEMBL16855838 | 0.88 | L3MBTL1 (0.45) | L3MBTL1S1PR1KDM1ARARARARB | |
| SCHEMBL9484258 | 0.88 | THRA (0.53) | L3MBTL1S1PR1RARARARBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087272-B2 | negative anisotropy of the dielectric constants; liquid-crystalline media and optical and electro-optical display elements | MERCK PATENT GMBH (DE) | 2006-08-08 | — | — | US | disclosed |
| US-20040106798-A1 | negative anisotropy of the dielectric constants; liquid-crystalline media and optical and electro-optical display elements | MERCK PATENT GMBH (DE) | 2004-06-03 | — | — | US | disclosed |
| EP-1373434-A1 | FLUORINATED FLUORENE DERIVATIVES | MERCK PATENT GmbH (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002079344-A1 | FLUORINATED FLUORENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106798-A1 | negative anisotropy of the dielectric constants; liquid-crystalline media and optical and electro-optical display elements | H1-0, F3, H1-2 | L3MBTL1 478/4885S1PR1 690/4885KDM1A 2501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.