Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23793645 | 0.84 | ESR1 (0.39) | ESR1ALDH1A1MAPK1HIF1ACYP2C19 | |
| SCHEMBL5827515 | 0.83 | ESR1 (0.38) | ESR1ALDH1A1MAPK1HIF1ACYP2C19 | |
| SCHEMBL5571046 | 0.81 | ALDH1A1 (0.56) | ESR1ALDH1A1MAPK1HIF1ACYP2C19 | |
| SCHEMBL10494911 | 0.81 | CYP2C19 (0.53) | ESR1ALDH1A1MAPK1HIF1ACYP2C19 | |
| SCHEMBL11519916 | 0.80 | KDM4E (0.44) | ESR1ALDH1A1MAPK1HIF1ACYP2C19 | |
| SCHEMBL8358088 | 0.79 | SLC6A2 (0.46) | ESR1ALDH1A1MAPK1HIF1ACYP2C19 | |
| SCHEMBL6349366 | 0.78 | ESR1 (0.50) | ESR1ALDH1A1MAPK1HIF1ACYP2C19 | |
| SCHEMBL11742611 | 0.77 | RXRA (0.43) | HIF1ATSHRCYP2C9KMT2ANPSR1 | |
| SCHEMBL10020195 | 0.76 | ESR1 (0.48) | ESR1ALDH1A1MAPK1HIF1ACYP2C19 | |
| SCHEMBL9248538 | 0.76 | ESR1 (0.48) | ESR1ALDH1A1MAPK1HIF1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795549-B2 | 1,2-alkane polyol-containing composition | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2017-10-24 | — | — | US | disclosed |
| US-20160045414-A1 | 1,2-ALKANE POLYOL-CONTAINING COMPOSITION | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2016-02-18 | — | — | US | disclosed |
| EP-2985017-A1 | 1,2-ALKANE POLYOL-CONTAINING COMPOSITION | Osaka Organic Chemical Ind., Ltd. (JP) | 2016-02-17 | — | — | EP | disclosed |
| CN-105142605-A | 1, 2-alkane polyol-containing composition | OSAKA ORGANIC CHEM IND | 2015-12-09 | — | — | CN | disclosed |
| EP-2546679-A1 | \"Three-dimensional dosimeter for penetrating radiation and method of use\ | Heuris Pharma LLC (US) | 2013-01-16 | — | — | EP | disclosed |
| US-7098463-B2 | Three-dimensional dosimeter for penetrating radiation and method of use | HEURIS PHARMA, LLC (US) | 2006-08-29 | — | — | US | disclosed |
| EP-1599743-A2 | THREE-DIMENTIONAL DOSIMETER FOR PENETRATING RADIATION AND METHOD OF USE | Heuris Pharma LLC (US) | 2005-11-30 | — | — | EP | disclosed |
| US-20040211917-A1 | Three-dimensional dosimeter for penetrating radiation and method of use | HEURIS PHARMA, LLC | 2004-10-28 | — | — | US | disclosed |
| WO-2004079393-A2 | THREE-DIMENTIONAL DOSIMETER FOR PENETRATING RADIATION AND METHOD OF USE | HEURIS PHARMA LLC (US) | 2004-09-16 | — | — | WO | disclosed |