Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943375 | 0.89 | — | — | |
| Alcohol SCHEMBL5865954 | 0.82 | — | — | |
| Alcohol SCHEMBL5865952 | 0.76 | LMNA (0.34) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11312836 | 0.72 | ALDH1A1 (0.46) | LMNATSHRALOX15 | |
| SCHEMBL28165020 | 0.72 | — | — | |
| SCHEMBL7629357 | 0.71 | — | — | |
| SCHEMBL677807 | 0.71 | LMNA (0.31) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9621020 | 0.70 | CYP2D6 (0.31) | LMNATSHRMAPT | |
| SCHEMBL9480623 | 0.69 | — | — | |
| Alcohol SCHEMBL11744996 | 0.69 | LMNA (0.46) | LMNACHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078049-B2 | Ultrafine emulsion containing a haloalkynyl derivative | L'OREAL (FR) | 2006-07-18 | — | — | US | claimed |
| US-20030073689-A1 | Ultrafine emulsion containing a haloalkynyl derivative | L'OREAL (FR) | 2003-04-17 | — | — | US | claimed |
| US-5374378-A | Flowable microbicidal agents | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-20 | — | — | US | disclosed |