Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524902 | 0.85 | GPR119 (0.56) | GPR119ALOX5APFEN1 | |
| SCHEMBL29757897 | 0.81 | GPR119 (0.60) | GPR119 | |
| SCHEMBL384986 | 0.81 | GPR119 (0.60) | GPR119 | |
| SCHEMBL25547495 | 0.77 | GPR119 (0.45) | GPR119KDM4EPKM | |
| SCHEMBL30452097 | 0.77 | GPR119 (0.45) | GPR119KDM4EPKM | |
| SCHEMBL22284364 | 0.77 | GPR119 (0.45) | GPR119KDM4EPKM | |
| SCHEMBL22284363 | 0.77 | GPR119 (0.45) | GPR119KDM4EPKM | |
| SCHEMBL8534574 | 0.77 | PIK3CD (0.51) | GPR119USP30 | |
| SCHEMBL22284447 | 0.76 | GPR119 (0.52) | GPR119KDM4EPKM | |
| SCHEMBL30451663 | 0.76 | GPR119 (0.52) | GPR119KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417124-A2 | SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR | Eli Lilly and Company (US) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010117979-A2 | SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR | ELI LILLY AND COMPANY (US) | 2010-10-14 | — | — | WO | disclosed |