Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.48 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.48 |
| ▸ | FEN1 | P39748 | 2/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29757897 | 0.93 | GPR119 (0.60) | GPR119CHRNA3CHEK2CHRNB1CHRNB2 | |
| SCHEMBL384986 | 0.93 | GPR119 (0.60) | GPR119CHRNA3CHEK2CHRNB1CHRNB2 | |
| SCHEMBL31071572 | 0.86 | GPR119 (0.53) | GPR119CHEK2 | |
| SCHEMBL586629 | 0.85 | GPR119 (0.44) | GPR119ALOX5APFEN1 | |
| SCHEMBL7526229 | 0.84 | GPR119 (0.51) | GPR119ALOX5APFEN1CHEK2SLC2A1 | |
| SCHEMBL19610292 | 0.83 | GPR119 (0.54) | GPR119ALOX5APFEN1CHEK2SLC2A1 | |
| SCHEMBL8534574 | 0.82 | PIK3CD (0.51) | GPR119 | |
| SCHEMBL7513551 | 0.82 | GPR119 (0.49) | GPR119ALOX5APFEN1CHEK2SLC2A1 | |
| SCHEMBL7524187 | 0.82 | GPR119 (0.49) | GPR119ALOX5APFEN1CHEK2SLC2A1 | |
| SCHEMBL21398088 | 0.82 | GPR119 (0.53) | GPR119ALOX5APFEN1CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151712-A1 | 3-pyrrolidinyloxy-3'-pyridyl ether compounds useful for controlling chemical synaptic transmission | LIN NAN-HORNG (US) | 2002-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151712-A1 | 3-pyrrolidinyloxy-3'-pyridyl ether compounds useful for controlling chemical synaptic transmission | GAP43, SLC18A2, GABRE | GPR119 604/4885CHRNA3 10/4885ALOX5AP 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.