Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28216352 | 0.87 | ALDH1A1 (0.52) | HSD11B1CYP2C19KMT2AMAPTHIF1A | |
| SCHEMBL8683368 | 0.87 | ALDH1A1 (0.52) | HSD11B1CYP2C19KMT2AMAPTHIF1A | |
| SCHEMBL164244 | 0.87 | ALDH1A1 (0.52) | HSD11B1CYP2C19KMT2AMAPTHIF1A | |
| Formaldehyde SCHEMBL28051418 | 0.85 | MAPT (0.48) | HSD11B1CYP2C19NR1I2KMT2AMAPT | |
| SCHEMBL28834712 | 0.85 | ALDH1A1 (0.50) | HSD11B1CYP2C19KMT2AMAPTHIF1A | |
| SCHEMBL6878084 | 0.85 | ALDH1A1 (0.50) | HSD11B1CYP2C19KMT2AMAPTHIF1A | |
| Methane SCHEMBL27871284 | 0.85 | ALDH1A1 (0.50) | HSD11B1CYP2C19KMT2AMAPTHIF1A | |
| Tert-Butanol SCHEMBL11434050 | 0.85 | ALDH1A1 (0.50) | HSD11B1CYP2C19KMT2AMAPTHIF1A | |
| SCHEMBL28362132 | 0.85 | ALDH1A1 (0.50) | HSD11B1CYP2C19KMT2AMAPTHIF1A | |
| SCHEMBL27760278 | 0.85 | ALDH1A1 (0.50) | HSD11B1CYP2C19KMT2AMAPTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7119056-B2 | Free-flowing, amphiphilic, non-ionic oligoesters | SASOL GERMANY GMBH (DE) | 2006-10-10 | — | — | US | disclosed |
| US-20050101667-A1 | Free-flowing, amphiphilic, non-ionic oligoesters | SASOL GERMANY GMBH (DE) | 2005-05-12 | — | — | US | disclosed |