Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 6/20 | 0.42 |
| ▸ | ABL1 | P00519 | 6/20 | 0.39 |
| ▸ | BCR | P11274 | 6/20 | 0.39 |
| ▸ | FLT3 | P36888 | 4/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.39 |
| ▸ | FLT1 | P17948 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3534641 | 0.89 | PDPK1 (0.43) | PDPK1ABL1BCRFLT3FGFR1 | |
| SCHEMBL5866748 | 0.86 | ITK (0.46) | PDPK1ABL1BCRFLT3FGFR1 | |
| SCHEMBL3533655 | 0.84 | MAPT (0.43) | PDPK1ABL1BCRFLT3FGFR1 | |
| SCHEMBL3532328 | 0.83 | PDPK1 (0.52) | PDPK1ABL1BCRFLT3FGFR1 | |
| SCHEMBL3532400 | 0.82 | FGFR1 (0.54) | PDPK1ABL1BCRFLT3FGFR1 | |
| SCHEMBL5866797 | 0.81 | PDPK1 (0.51) | PDPK1ABL1BCRFLT3FGFR1 | |
| SCHEMBL15868927 | 0.80 | FGFR1 (0.45) | PDPK1ABL1BCRFLT3FGFR1 | |
| SCHEMBL6582455 | 0.80 | ABL1 (0.53) | ABL1BCRFLT3FGFR1FLT1 | |
| SCHEMBL3535364 | 0.80 | FLT3 (0.42) | PDPK1ABL1FLT3FGFR1FLT1 | |
| SCHEMBL3539832 | 0.79 | FGFR1 (0.42) | PDPK1ABL1BCRFLT3FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064215-B2 | Indazole benzimidazole compounds | CHIRON CORPORATION (US) | 2006-06-20 | — | — | US | disclosed |