Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5867014 | 0.81 | CRHR1 (0.35) | CRHR1RAPGEF4 | |
| SCHEMBL8813320 | 0.76 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL5844119 | 0.67 | CRHR1 (0.59) | CRHR1RAPGEF4 | |
| SCHEMBL5866772 | 0.66 | CRHR1 (0.35) | CRHR1RAPGEF4 | |
| SCHEMBL5844351 | 0.65 | CRHR1 (0.53) | CRHR1RAPGEF4 | |
| SCHEMBL5844541 | 0.65 | CRHR1 (0.50) | CRHR1RAPGEF4 | |
| SCHEMBL5845092 | 0.65 | CRHR1 (0.50) | CRHR1RAPGEF4 | |
| SCHEMBL7013499 | 0.63 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL7480702 | 0.63 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL5866766 | 0.63 | CRHR1 (0.38) | CRHR1RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6992188-B1 | Substituted heterocyclic derivatives | PFIZER, INC. (US) | 2006-01-31 | — | — | US | disclosed |
| EP-0778277-A1 | Substituted heterocyclic derivatives as CRF antagonists | PFIZER INC. (US) | 1997-06-11 | — | — | EP | disclosed |