Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.55 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.55 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13588551 | 1.00 | EPHX1 (0.55) | EPHX1SLC1A3SLC1A2SLC1A1SLC6A2 | |
| SCHEMBL23960529 | 1.00 | EPHX1 (0.55) | EPHX1SLC1A3SLC1A2SLC1A1SLC6A2 | |
| SCHEMBL27806639 | 0.88 | EPHX1 (0.62) | EPHX1SLC1A3SLC1A2SLC1A1ALPI | |
| SCHEMBL5511480 | 0.84 | SLC1A3 (0.63) | SLC1A3SLC1A2SLC1A1NPC1RAB9A | |
| SCHEMBL883357 | 0.84 | SLC1A3 (0.63) | SLC1A3SLC1A2SLC1A1NPC1RAB9A | |
| SCHEMBL12477240 | 0.84 | ACE (0.59) | EPHX1SLC1A3SLC1A2SLC1A1SLC6A2 | |
| SCHEMBL21261466 | 0.83 | TAAR1 (0.55) | EPHX1SLC6A2TAAR1SLC7A5ACE | |
| SCHEMBL12184990 | 0.83 | TAAR1 (0.55) | EPHX1SLC6A2TAAR1SLC7A5ACE | |
| SCHEMBL12118692 | 0.83 | EPHX1 (0.51) | EPHX1PTGS1KMT2A | |
| SCHEMBL19647227 | 0.82 | ALPI (0.52) | SLC1A3SLC1A2SLC1A1SLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195183-A1 | COMPOSITIONS AND METHODS FOR INHIBITING PROTEIN EMBRYONIC ECTODERM DEVELOPMENT ACTIVITY AND TREATING DISEASE | EXO THERAPEUTICS, INC. (US) | 2021-09-30 | — | — | WO | disclosed |
| US-20110028447-A1 | INDAZOLE DERIVATIVES | PFIZER INC. | 2011-02-03 | — | — | US | disclosed |
| US-7154004-B2 | Catalytic transamidation and amide metathesis under moderate conditions | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-12-26 | — | — | US | disclosed |
| US-20040230078-A1 | Catalytic transamidation and amide metathesis under moderate conditions | NATIONAL SCIENCE FOUNDATION | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040230078-A1 | Catalytic transamidation and amide metathesis under moderate conditions | NAAA, NIT2, NAT10 | EPHX1 2739/4885SLC1A3 1107/4885SLC1A2 1066/4885 |
| US-20110028447-A1 | INDAZOLE DERIVATIVES | CNR1, CNR2, GPR119 | EPHX1 1179/4885SLC1A3 1922/4885SLC1A2 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.