Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5866990 | 0.78 | CRHR1 (0.66) | CRHR1 | |
| SCHEMBL5866781 | 0.77 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL7216722 | 0.74 | CRHR1 (0.54) | CRHR1HCAR3 | |
| SCHEMBL7218772 | 0.66 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL7218775 | 0.66 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL5844779 | 0.65 | CRHR1 (0.57) | CRHR1 | |
| SCHEMBL5843292 | 0.65 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL7224230 | 0.65 | CRHR1 (0.85) | CRHR1 | |
| SCHEMBL7629851 | 0.64 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL16606730 | 0.64 | CRHR1 (1.00) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6992188-B1 | Substituted heterocyclic derivatives | PFIZER, INC. (US) | 2006-01-31 | — | — | US | disclosed |
| EP-0778277-B1 | Substituted heterocyclic derivatives as CRF antagonists | PFIZER (US) | 2003-06-25 | — | — | EP | disclosed |
| EP-0778277-A1 | Substituted heterocyclic derivatives as CRF antagonists | PFIZER INC. (US) | 1997-06-11 | — | — | EP | disclosed |