Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369262 | 0.88 | DPP4 (0.57) | DPP4CYP3A4 | |
| SCHEMBL3369445 | 0.86 | DPP4 (1.00) | DPP4CYP3A4 | |
| SCHEMBL3369601 | 0.83 | DPP4 (1.00) | DPP4CYP3A4 | |
| SCHEMBL3369384 | 0.79 | DPP4 (1.00) | DPP4CYP3A4 | |
| SCHEMBL3369005 | 0.79 | DPP4 (1.00) | DPP4CYP3A4 | |
| SCHEMBL4475821 | 0.78 | DPP4 (0.83) | DPP4CYP3A4 | |
| SCHEMBL3369578 | 0.77 | DPP4 (1.00) | DPP4CYP3A4 | |
| SCHEMBL3368680 | 0.76 | DPP4 (1.00) | DPP4CYP3A4 | |
| SCHEMBL4471810 | 0.76 | DPP4 (0.76) | DPP4CYP3A4 | |
| SCHEMBL3369367 | 0.76 | DPP4 (0.59) | DPP4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022718-B2 | Pyridine and pyrimidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2006-04-04 | — | — | US | disclosed |
| US-20050143405-A1 | Pyridine and pyrimidine derivatives | BOEHRINGER MARKUS (CH) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143405-A1 | Pyridine and pyrimidine derivatives | DPP4, GPR119, PDXK | DPP4 1/4885CYP3A4 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.