SCHEMBL586749

SCHEMBL586749

CCCCCCCC[Al](CCCCCCCC)Oc1c(C(C)(C)C)cccc1C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.33
KCNH2 Q12809 2/20 0.33
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.31
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
NLRP3 Q96P20 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76761 0.87 CA2 (0.33) CA2KCNH2ALDH1A1TSHRPPARG
SCHEMBL6054742 0.87 CA2 (0.33) CA2KCNH2ALDH1A1TSHRPPARG
SCHEMBL585846 0.83 CYP3A4 (0.36) CA2ALDH1A1
SCHEMBL8760276 0.80 CA2 (0.35) CA2ALDH1A1TSHRNLRP3GABRA1
SCHEMBL585123 0.79 CA2 (0.40) CA2ALDH1A1TSHRNLRP3GABRA1
SCHEMBL2279867 0.75 CYP2D6 (0.38) CA2ALDH1A1
SCHEMBL1560489 0.73 SOAT1 (0.40) TSHR
SCHEMBL27934690 0.72 ALDH1A1 (0.46) CA2KCNH2ALDH1A1TSHR
SCHEMBL938249 0.72 CA2 (0.40) CA2ALDH1A1TSHRNLRP3GABRA1
SCHEMBL585168 0.71 CA2 (0.36) CA2ALDH1A1TSHRGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6767976-B2 POLYMERIZING METHACRYLIC ESTER OR ACRYLIC ESTER ANIONICALLY, USING A POLYMERIZATION INITIATOR COMPRISING ADDITION REACTION PRODUCT OF CONJUGATED DIENE COMPOUND AND ORGANIC ALKALI METAL COMPOUND AND TERTIARY ORGANOALUMINUM COMPOUND KURARAY CO., LTD. (JP) 2004-07-27 US claimed
US-12281185-B2 Anionic polymerization process and polymer production method KURARAY CO., LTD. (JP) 2025-04-22 US disclosed
EP-3845570-B1 ANIONIC POLYMERIZATION PROCESS AND POLYMER PRODUCTION METHOD KURARAY CO (JP) 2024-10-09 EP disclosed
US-11845818-B2 Active energy ray crosslinkable thermoplastic polymer and composition containing the same KURARAY CO., LTD. (JP) 2023-12-19 US disclosed
CN-113453898-B Active energy ray-crosslinkable thermoplastic polymer and composition containing same 株式会社可乐丽 2023-10-20 CN disclosed
US-11613602-B2 (Meth)acrylic block copolymer and active energy ray curable composition containing the same KURARAY CO., LTD. (JP) 2023-03-28 US disclosed
CN-111356712-B (meth) acrylic block copolymer and active energy ray-curable composition containing same 株式会社可乐丽 2023-01-31 CN disclosed
CN-112601765-B Anionic polymerization method and method for producing polymer 株式会社可乐丽 2022-10-25 CN disclosed
EP-3587490-B1 METHACRYLIC RESIN COMPOSITION AND USE THEREOF KURARAY CO (JP) 2022-10-12 EP disclosed
US-20220251249-A1 ACTIVE ENERGY RAY CROSSLINKABLE THERMOPLASTIC POLYMER AND COMPOSITION CONTAINING THE SAME KURARAY CO., LTD. (JP) 2022-08-11 US disclosed
EP-1078942-B1 Anionic polymerization process, and process for producing a polymer by the anionic polymerization process KURARAY CO (JP) 2006-06-07 EP disclosed
EP-1085029-B1 Process for polymerizing a methacrylic ester or an acrylic ester KURARAY CO (JP) 2005-12-14 EP disclosed
US-6831144-B2 Containing, in addition to an anionic polymerization initiator, a organoaluminum compound containing aryloxy groups, a Lewis base, and an ether or a tertiary amine KURARAY CO., LTD. (JP) 2004-12-14 US disclosed
US-6767976-B2 POLYMERIZING METHACRYLIC ESTER OR ACRYLIC ESTER ANIONICALLY, USING A POLYMERIZATION INITIATOR COMPRISING ADDITION REACTION PRODUCT OF CONJUGATED DIENE COMPOUND AND ORGANIC ALKALI METAL COMPOUND AND TERTIARY ORGANOALUMINUM COMPOUND KURARAY CO., LTD. (JP) 2004-07-27 US disclosed
US-20030204033-A1 Process for polymerizing a methacrylic ester or an acrylic ester KURARAY CO., LTD. (JP) 2003-10-30 US disclosed
US-6630554-B1 Methacrylic ester or an acrylic ester is anionically polymerized, using a polymerization initiator compound omprising an addition reaction product of a conjugated diene compound and an organic alkali metal compound, in the presence KURARAY CO., LTD. (JP) 2003-10-07 US disclosed
US-20030134998-A1 Anionic polymerization process, and process for producing a polymer by the anionic polymerization process KURARAY CO. LTD. (JP) 2003-07-17 US disclosed
US-6555637-B1 In anionic polymerization using an anionic polymerization initiator, a tertiary organoaluminum compound (A) having AL-O-Ar (Ar= aromatic ring) formula, and a Lewis base (B) selected from the group containing tertiary polyamine KURARAY CO., LTD. (JP) 2003-04-29 US disclosed
EP-1085029-A1 Process for polymerizing a methacrylic ester or an acrylic ester KURARAY CO., LTD. (JP) 2001-03-21 EP disclosed
EP-1078942-A1 Anionic polymerization process, and process for producing a polymer by the anionic polymerization process KURARAY CO., LTD. (JP) 2001-02-28 EP disclosed