Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CAD | P27708 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810181 | 1.00 | ACE (0.43) | ACECPB2CYP1A2NOD1KMT2A | |
| SCHEMBL11025288 | 0.95 | CPB2 (0.48) | ACECPB2CYP1A2NOD1KMT2A | |
| SCHEMBL11025294 | 0.95 | CPB2 (0.48) | ACECPB2CYP1A2NOD1KMT2A | |
| SCHEMBL7271367 | 0.84 | ACE (0.57) | ACENOD1KMT2A | |
| SCHEMBL9773222 | 0.84 | ACE (0.57) | ACENOD1KMT2A | |
| SCHEMBL7271357 | 0.84 | ACE (0.57) | ACENOD1KMT2A | |
| SCHEMBL9773243 | 0.84 | ACE (0.57) | ACENOD1KMT2A | |
| SCHEMBL9702204 | 0.84 | ACE (0.57) | ACENOD1KMT2A | |
| SCHEMBL1992431 | 0.83 | ACE (0.49) | ACEKMT2APOLBLMNAL3MBTL1 | |
| SCHEMBL13482629 | 0.83 | ACE (0.49) | ACEKMT2APOLBLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017567-A | Steroid antiinflammatory | SCHERING CORPORATION (US) | 1991-05-21 | — | — | US | disclosed |
| US-4778795-A | Carboxyalkyl dipeptides as antiglaucoma agents | SCHERING CORPORATION (US) | 1988-10-18 | — | — | US | disclosed |
| US-4616012-A | BENZOTHIADIZINYL AND QUINAZOLINYL DERIVATIVES | SCHERING CORPORATION (US) | 1986-10-07 | — | — | US | disclosed |
| US-4559340-A | DIURETICS; GLAUCOMA | SCHERING CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |