Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | PLK1 | P53350 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5870589 | 0.80 | CYP2C19 (0.65) | SMN1; SMN2HSD17B10CYP2C19KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL5869997 | 0.79 | CYP2C19 (0.62) | SMN1; SMN2HSD17B10CYP2C19KMT2AKDM4E | |
| SCHEMBL5870372 | 0.79 | CYP2C19 (0.44) | SMN1; SMN2HSD17B10CYP2C19KMT2AKDM4E | |
| SCHEMBL6499135 | 0.79 | CYP2C19 (0.44) | SMN1; SMN2HSD17B10CYP2C19KDM4EALDH1A1 | |
| SCHEMBL5870140 | 0.75 | KMT2A (0.54) | SMN1; SMN2HSD17B10KMT2AKDM4EMAPT | |
| SCHEMBL5870445 | 0.75 | KDM4E (0.58) | SMN1; SMN2HSD17B10KMT2AKDM4EALDH1A1 | |
| SCHEMBL5870304 | 0.74 | ALDH1A1 (0.44) | SMN1; SMN2HSD17B10KMT2AKDM4EMAPT | |
| SCHEMBL26015672 | 0.74 | SMN1; SMN2 (0.67) | SMN1; SMN2HSD17B10KMT2AKDM4EMAPT | |
| SCHEMBL15074569 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2HSD17B10KMT2AKDM4EMAPT | |
| SCHEMBL11551784 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2HSD17B10CYP2C19KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078528-B2 | Biimidazole diamide anion binding agents | EAST CAROLINA UNIVERSITY (US) | 2006-07-18 | — | — | US | disclosed |
| US-20050004370-A1 | Biimidazole diamide anion binding agents | EAST CAROLINA UNIVERSITY | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004370-A1 | Biimidazole diamide anion binding agents | ABCG2, BRI3BP, SLCO1B3 | SMN1; SMN2 4649/4885PLK1 1324/4885HSD17B10 2912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.