Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499135 | 0.81 | CYP2C19 (0.44) | CYP2C19HSD17B10LMNAKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5869997 | 0.81 | CYP2C19 (0.62) | CYP2C19HSD17B10LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5870375 | 0.79 | SMN1; SMN2 (0.42) | CYP2C19HSD17B10LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5870445 | 0.77 | KDM4E (0.58) | HSD17B10LMNAKDM4ESMN1; SMN2GAA | |
| SCHEMBL2101530 | 0.75 | LMNA (0.45) | CYP2C19HSD17B10LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL7325537 | 0.75 | CYP2C19 (0.39) | CYP2C19HSD17B10LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL14692540 | 0.74 | CYP2C19 (0.57) | CYP2C19HSD17B10LMNAKDM4EALDH1A1 | |
| SCHEMBL5870451 | 0.74 | HPGD (0.41) | CYP2C19HSD17B10KDM4ESMN1; SMN2GAA | |
| SCHEMBL5870140 | 0.72 | KMT2A (0.54) | HSD17B10KDM4ESMN1; SMN2GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11004255 | 0.71 | GABRR1 (0.44) | CYP2C19HSD17B10LMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078528-B2 | Biimidazole diamide anion binding agents | EAST CAROLINA UNIVERSITY (US) | 2006-07-18 | — | — | US | disclosed |
| US-20050004370-A1 | Biimidazole diamide anion binding agents | EAST CAROLINA UNIVERSITY | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004370-A1 | Biimidazole diamide anion binding agents | ABCG2, BRI3BP, SLCO1B3 | CYP2C19 2427/4885HSD17B10 2912/4885LMNA 4654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.