Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 6/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5870291 | 0.78 | CTSS (0.53) | CTSS | |
| SCHEMBL14347626 | 0.73 | NAAA (0.40) | CTSSNAAA | |
| Hydrochloric Acid SCHEMBL5627174 | 0.72 | NAAA (0.39) | CTSSNAAA | |
| Hydrochloric Acid SCHEMBL5627163 | 0.72 | NAAA (0.39) | CTSSNAAA | |
| SCHEMBL5870402 | 0.68 | CTSS (0.42) | CTSS | |
| SCHEMBL14347630 | 0.66 | CTSS (0.55) | CTSSNAAA | |
| SCHEMBL5870430 | 0.65 | CTSS (0.42) | CTSSNAAA | |
| SCHEMBL5870500 | 0.64 | CTSS (0.34) | CTSSNAAA | |
| SCHEMBL294162 | 0.63 | CTSC (0.35) | — | |
| SCHEMBL7034077 | 0.63 | AAK1 (0.37) | NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132449-B2 | Inhibitors of cruzipain and other cysteine proteases | AMURA THERAPEUTICS LIMITED (GB) | 2006-11-07 | — | — | US | disclosed |
| US-20040127424-A1 | Inhibitors of cruzipain and other cysteine proteases | AMURA THERAPUTICS LIMITED (GB) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127424-A1 | Inhibitors of cruzipain and other cysteine proteases | CPN1, CTRL, CPA1 | LTA4H 1316/4885CTSS 24/4885NAAA 1250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.