Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.57 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.57 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 6/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8251179 | 0.82 | PSMB1 (0.69) | ACACBPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL2741674 | 0.80 | PSMB1 (0.68) | KDM4EPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL2741675 | 0.80 | PSMB1 (0.68) | KDM4EPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL8245067 | 0.80 | PSMB1 (0.67) | ACACBKDM4EPSMB1PSMB5PSMB2 | |
| Hydrochloric Acid SCHEMBL228735 | 0.79 | PSMB1 (0.66) | KDM4EPSMB1PSMB5PSMB2HRH3 | |
| Hydrochloric Acid SCHEMBL228395 | 0.79 | PSMB1 (0.66) | KDM4EPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL7240783 | 0.79 | PSMB1 (0.65) | KDM4EPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL16379389 | 0.79 | PSMB1 (0.61) | ACACBKDM4EPSMB1PSMB5PSMB2 | |
| SCHEMBL31754269 | 0.79 | ITGB3 (0.60) | ACACBKDM4EPSMB1PSMB5PSMB2 | |
| SCHEMBL26399344 | 0.79 | ITGB3 (0.60) | ACACBKDM4EPSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105679-B2 | Heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators | KANOJIA RAMESH M | 2006-09-12 | — | — | US | disclosed |