Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2114742 | 0.87 | APP (0.75) | APPNPC1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5871989 | 0.87 | APP (0.75) | APPNPC1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7835738 | 0.81 | NPC1 (0.47) | APPNPC1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5475379 | 0.79 | TSHR (0.35) | APPNPC1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28684400 | 0.77 | APP (0.67) | APPNPC1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2747094 | 0.76 | APP (0.57) | APPNPC1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL15009036 | 0.76 | APP (0.57) | APPNPC1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL10437173 | 0.76 | APP (0.57) | APPNPC1ALDH1A1CYP1A2CYP3A4 | |
| Diphenylacetylene SCHEMBL960609 | 0.76 | APP (1.00) | APPNPC1ALDH1A1CYP1A2CYP3A4 | |
| Diphenylacetylene SCHEMBL29188592 | 0.76 | APP (1.00) | APPNPC1ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7381850-B2 | Multifunctional unsymmetrically substituted monomers and polyarylene compositions therefrom | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-20060267000-A1 | Multifunctional unsymmetrically substituted monomers and polyarylene compositions therefrom | DOW GLOBAL TECHNOLOGIES INC. | 2006-11-30 | — | — | US | disclosed |
| EP-1542869-A4 | MOLECULAR SCALE ELECTRONIC DEVICES | UNIV YALE (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1542869-A2 | MOLECULAR SCALE ELECTRONIC DEVICES | Yale University (US) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004089862-A2 | MULTIFUNCTIONAL UNSYMMETRICALLY SUBSTITUTED MONOMERS AND POLYARYLENE COMPOSITIONS THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-10-21 | — | — | WO | disclosed |
| US-6756605-B1 | Molecular scale electronic devices | YALE UNIVERSITY | 2004-06-29 | — | — | US | disclosed |
| WO-2001027972-A9 | MOLECULAR SCALE ELECTRONIC DEVICES | UNIV YALE (US) | 2002-11-14 | — | — | WO | disclosed |
| WO-2001027972-A2 | MOLECULAR SCALE ELECTRONIC DEVICES | YALE UNIVERSITY (US) | 2001-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060267000-A1 | Multifunctional unsymmetrically substituted monomers and polyarylene compositions therefrom | WASF2, DDT, CAD | APP 2993/4885NPC1 4867/4885ALDH1A1 1809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.