Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | RRM1 | P23921 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | OTC | P00480 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | ARG1 | P05089 | 1/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872015 | 0.81 | DPP7 (0.41) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL17813676 | 0.80 | DPP7 (0.40) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL607463 | 0.79 | DPP7 (0.44) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL3169670 | 0.79 | DPP7 (0.44) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL18866881 | 0.79 | DPP7 (0.44) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| L-Citrulline SCHEMBL7526760 | 0.79 | GSR (0.60) | GNAI3GNAO1GNAI1NOS1OTC | |
| L-Citrulline SCHEMBL7526767 | 0.79 | GSR (0.60) | GNAI3GNAO1GNAI1NOS1OTC | |
| L-Citrulline SCHEMBL9107741 | 0.77 | GSR (0.69) | GNAI3GNAO1GNAI1NOS1OTC | |
| L-Citrulline SCHEMBL9107735 | 0.77 | GSR (0.69) | GNAI3GNAO1GNAI1NOS1OTC | |
| SCHEMBL13444714 | 0.77 | DPP7 (0.53) | GNAI3GNAO1GNAI1DPP7RRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001984-B2 | Di-, tri-, and tetra-peptides having antiangiogenic activity | ABBOTT LABORATORIES (US) | 2006-02-21 | — | — | US | disclosed |
| US-20050215484-A1 | Di-, tri-, and tetra-peptides having antiangiogenic activity | HAVIV FORTUNA | 2005-09-29 | — | — | US | disclosed |