Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | OTC | P00480 | 1/20 | 0.40 |
| ▸ | ARG1 | P05089 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | RRM1 | P23921 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872308 | 0.85 | DPP7 (0.39) | DPP7OTCDDAH1GNAI3GNAO1 | |
| SCHEMBL17813676 | 0.83 | DPP7 (0.40) | DPP7OTCARG1DDAH1GNAI3 | |
| SCHEMBL14148334 | 0.82 | DPP7 (0.42) | DPP7OTCARG1DDAH1GNAI3 | |
| SCHEMBL607463 | 0.82 | DPP7 (0.44) | DPP7OTCARG1DDAH1GNAI3 | |
| SCHEMBL18866881 | 0.82 | DPP7 (0.44) | DPP7OTCARG1DDAH1GNAI3 | |
| SCHEMBL3169670 | 0.82 | DPP7 (0.44) | DPP7OTCARG1DDAH1GNAI3 | |
| SCHEMBL5872019 | 0.81 | GNAI3 (0.44) | DPP7OTCARG1DDAH1GNAI3 | |
| SCHEMBL7763876 | 0.81 | DPP7 (0.38) | DPP7OTCARG1DDAH1GNAI3 | |
| L-Citrulline SCHEMBL15909605 | 0.80 | OTC (0.59) | OTCARG1DDAH1ALOX15BLM | |
| L-Citrulline SCHEMBL9070200 | 0.80 | OTC (0.59) | OTCARG1DDAH1ALOX15BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001984-B2 | Di-, tri-, and tetra-peptides having antiangiogenic activity | ABBOTT LABORATORIES (US) | 2006-02-21 | — | — | US | disclosed |
| US-20050215484-A1 | Di-, tri-, and tetra-peptides having antiangiogenic activity | HAVIV FORTUNA | 2005-09-29 | — | — | US | disclosed |