Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL5872365 | 0.95 | ALDH1A1 (0.48) | ALDH1A1TSHRLMNATDP1EGFR | |
| Styrene SCHEMBL5872235 | 0.89 | ALDH1A1 (0.54) | ALDH1A1TSHRLMNATDP1PSIP1 | |
| Styrene SCHEMBL5872292 | 0.83 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1PSIP1HDAC8 | |
| Styrene SCHEMBL11801013 | 0.82 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNATDP1EGFR | |
| Styrene SCHEMBL10715462 | 0.82 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNATDP1EGFR | |
| Styrene SCHEMBL1194200 | 0.82 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNATDP1EGFR | |
| Styrene SCHEMBL9614715 | 0.81 | ALDH1A1 (0.45) | ALDH1A1TSHRLMNATDP1EGFR | |
| Dodecane SCHEMBL27503014 | 0.81 | ALDH1A1 (0.64) | ALDH1A1TSHRLMNATDP1EGFR | |
| Hexadecane SCHEMBL27958494 | 0.81 | ALDH1A1 (0.64) | ALDH1A1TSHRLMNATDP1EGFR | |
| Styrene SCHEMBL1074288 | 0.81 | ALDH1A1 (0.64) | ALDH1A1TSHRLMNATDP1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559198-B2 | A contact lens comprising a copolymer consisting essentially of from about 25 to about 60 weight percent of a ethylenically unsaturated fluorosulfone ester monomer having the general formula comonomer selected from the group consisting of | NOVICKY NICK (CA) | 2003-05-06 | — | — | US | claimed |
| US-20030027886-A1 | Fluorocarbon-sulfone hydrophilic contact lenses, optical medical devices and compositions thereof | NOVICKY NICK (CA) | 2003-02-06 | — | — | US | claimed |
| EP-0231572-B1 | Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof | PROGRESSIVE OPTICAL RES LTD (CA) | 1994-11-02 | — | — | EP | claimed |
| US-4748224-A | Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof | Devou, Maureen J. (CA) | 1988-05-31 | — | — | US | claimed |
| EP-0231572-A2 | Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof | PROGRESSIVE OPTICAL RESEARCH LTD. (CA) | 1987-08-12 | — | — | EP | claimed |
| US-7098282-B2 | Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof | NOVICKY NICK | 2006-08-29 | — | — | US | disclosed |
| US-20050176907-A1 | Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof | NOVICKY NICK (CA) | 2005-08-11 | — | — | US | disclosed |
| EP-1455201-A1 | Fluorosulfone-silicone hydrogel RGP contact lenses, optical medical devices and compositions thereof | Novicky, Nick N. (CA) | 2004-09-08 | — | — | EP | disclosed |
| US-6559198-B2 | A contact lens comprising a copolymer consisting essentially of from about 25 to about 60 weight percent of a ethylenically unsaturated fluorosulfone ester monomer having the general formula comonomer selected from the group consisting of | NOVICKY NICK (CA) | 2003-05-06 | — | — | US | disclosed |
| US-20030027886-A1 | Fluorocarbon-sulfone hydrophilic contact lenses, optical medical devices and compositions thereof | NOVICKY NICK (CA) | 2003-02-06 | — | — | US | disclosed |
| EP-0231572-B1 | Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof | PROGRESSIVE OPTICAL RES LTD (CA) | 1994-11-02 | — | — | EP | disclosed |
| US-5093447-A | Contact lenses | NOVICKY NICK N (CA) | 1992-03-03 | — | — | US | disclosed |
| US-4948855-A | COPOLYMER OF UNSATURATED SILOXANYLALKOXYESTER AND VINYL SILFONE | PROGRESSIVE CHEMICAL RESEARCH, LTD. (CA) | 1990-08-14 | — | — | US | disclosed |
| US-4861850-A | CONTACT LENSES | PROGRESSIVE CHEMICAL RESEARCH, LTD. (CA) | 1989-08-29 | — | — | US | disclosed |
| US-4748224-A | Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof | Devou, Maureen J. (CA) | 1988-05-31 | — | — | US | disclosed |
| US-4743106-A | POLYMER HAVING AN ORGANOSILOXANYLALKOXY ESTER OF (METH)ACRYLIC ACID MONOMER; MACHINING | Devou, Maureen J. (CA) | 1988-05-10 | — | — | US | disclosed |
| EP-0231572-A2 | Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof | PROGRESSIVE OPTICAL RESEARCH LTD. (CA) | 1987-08-12 | — | — | EP | disclosed |